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IPR005913 is a dTDP-4-dehydrorhamnose reductase family.
<p>dTDP-4-dehydrorhamnose reductase ([ec:1.1.1.133]) catalyses the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose, which is the final step in the conversion of dTDP-D-glucose to dTDP-L-rhamnose [[cite:PUB00071248]]. dTDP-rhamnose is essential for growth of mycobacteria [[cite:PUB00071249]]. dTDP-L-rhamnose is the precursor of L-Rhamnose (L-Rha), a component of the lipopolysaccharide (LPS) core and several O antigen polysaccharides of Pseudomonas [[cite:PUB00071250]].</p> <p>Methionine adenosyltransferase 2 subunit beta (MAT2B) also belongs to this family. It is the regulatory subunit of MAT2A, an enzyme that catalyses the formation of S-adenosylmethionine (AdoMet) from methionine and ATP [[cite:PUB00071251]]. Also in this family is the probable dTDP-4,6-dihydroxy-2-methyloxan-3-one 4-ketoreductase (oleU) from<i>Streptomyces antibioticus</i>, which is required for the biosynthesis of the aglycone antibiotic oleandomycin [[cite:PUB00089648]].</p>
This description is obtained from EB-eye REST.
| Transcript | Name | Description | Predicted domains | Domain count |
|---|---|---|---|---|
| – | Methionine adenosyltransferase 2 subunit beta [Medicago truncatula] gi|357514671|ref|XP_003627624.1| | 8 |
A list of co-occurring predicted domains within the L. japonicus gene space:
| Predicted domain | Source | Observations | Saturation (%) |
|---|---|---|---|
| SSF51735 | SUPERFAMILY | 1 | 100.00 |