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IPR006003 is a FGGY carbohydrate kinase, pentulose kinase.
<p>This entry represents a subfamily of the FGGY family of carbohydrate kinases, including FGGY carbohydrate kinase domain-containing proteins from mammals and D-ribulokinase YDR109C from S. cerevisiae, which catalyse ATP-dependent phosphorylation of D-ribulose at C-5 to form D-ribulose 5-phosphate [[cite:PUB00099623]]. These proteins may function in a metabolite repair mechanism by preventing toxic accumulation of free D-ribulose formed by non-specific phosphatase activities, and may also play a role in regulating D-ribulose 5-phosphate recycling in the pentose phosphate pathway.</p> <p>This subfamily is closely related to a set of ribulose kinases, and many members are designated ribitol kinase. However, the member from Klebsiella pneumoniae, rbtK, from a ribitol catabolism operon, accepts D-ribulose and to a lesser extent D-arabinitol and ribitol [[cite:PUB00007926]].</p>
This description is obtained from EB-eye REST.
GO predictions are based solely on the InterPro-to-GO mappings published by EMBL-EBI, which are in turn based on the mapping of predicted domains to the InterPro dataset. The InterPro-to-GO mapping was last updated on , while the GO metadata was last updated on .
| GO term | Namespace | Name | Definition | Relationships |
|---|---|---|---|---|
| Biological process | Carbohydrate metabolic process | The chemical reactions and pathways involving carbohydrates, any of a group of organic compounds based of the general formula Cx(H2O)y. Includes the formation of carbohydrate derivatives by the addition of a carbohydrate residue to another molecule. | ||
| Molecular function | Phosphotransferase activity, alcohol group as acceptor | Catalysis of the transfer of a phosphorus-containing group from one compound (donor) to an alcohol group (acceptor). |
| Transcript | Name | Description | Predicted domains | Domain count |
|---|---|---|---|---|
| – | PREDICTED: FGGY carbohydrate kinase domain-containing protein-like isoform X1 [Cicer arietinum] gi|502150178|ref|XP_004507826.1| | 9 | ||
| – | Glycerol kinase; TAIR: AT4G30310.2 FGGY family of carbohydrate kinase; Swiss-Prot: sp|Q6DCD1|FGGY_XENLA FGGY carbohydrate kinase domain-containing protein; TrEMBL-Plants: tr|A0A1J7GZV6|A0A1J7GZV6_LUPAN Uncharacterized protein; Found in the gene: LotjaGi4g1v0298300 | 16 | ||
| – | Glycerol kinase; TAIR: AT4G30310.3 FGGY family of carbohydrate kinase; Swiss-Prot: sp|Q6DCD1|FGGY_XENLA FGGY carbohydrate kinase domain-containing protein; TrEMBL-Plants: tr|I1MST3|I1MST3_SOYBN Uncharacterized protein; Found in the gene: LotjaGi4g1v0298300 | 13 | ||
| – | Glycerol kinase; TAIR: AT4G30310.2 FGGY family of carbohydrate kinase; Swiss-Prot: sp|Q6DCD1|FGGY_XENLA FGGY carbohydrate kinase domain-containing protein; TrEMBL-Plants: tr|I1MST3|I1MST3_SOYBN Uncharacterized protein; Found in the gene: LotjaGi4g1v0298300 | 13 | ||
| – | Glycerol kinase; TAIR: AT4G30310.2 FGGY family of carbohydrate kinase; Swiss-Prot: sp|Q6DCD1|FGGY_XENLA FGGY carbohydrate kinase domain-containing protein; TrEMBL-Plants: tr|I1MST3|I1MST3_SOYBN Uncharacterized protein; Found in the gene: LotjaGi4g1v0298300 | 13 | ||
| – | Glycerol kinase; TAIR: AT4G30310.2 FGGY family of carbohydrate kinase; Swiss-Prot: sp|Q6DCD1|FGGY_XENLA FGGY carbohydrate kinase domain-containing protein; TrEMBL-Plants: tr|I1MST3|I1MST3_SOYBN Uncharacterized protein; Found in the gene: LotjaGi4g1v0298300 | 12 |
A list of co-occurring predicted domains within the L. japonicus gene space:
| Predicted domain | Source | Observations | Saturation (%) |
|---|---|---|---|
| cd07782 | CDD | 1 | 16.67 |