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IPR018485

Source: InterPro

Description

IPR018485 is a Carbohydrate kinase FGGY, C-terminal.

<p>This entry represents the C-terminal domain of these proteins. It adopts a ribonuclease H-like fold and is structurally related to the N-terminal domain [[cite:PUB00005161], [cite:PUB00019551]].</p> <p>FGGY carbohydrate kinases carry out ATP-dependent phosphorylation on one out of at least nine distinct sugar substrates [[cite:PUB00080793]]. These enzymes include L-ribulokinase ([ec:2.7.1.16]) (gene araB); Erythriol kinase ([ec:2.7.1.27]) (gene eryA); L-fucolokinase ([ec:2.7.1.51]) (gene fucK); gluconokinase ([ec:2.7.1.12]) (gene gntK); glycerol kinase ([ec:2.7.1.30]) (gene glpK); xylulokinase ([ec:2.7.1.17]) (gene xylB); L-xylulose kinase ([ec:2.7.1.53]) (gene lyxK), D-ribulokinase ([ec:2.7.1.47]) (gene rbtK); and rhamnulokinase ([ec:2.7.1.5]) (gene rhaB). This family also contains a divergent subfamily functioning in quorum sensing, which phosphorylates AI-2, a bacterial signaling molecule derived from 4,5-dihydroxy-2,3-pentanedione (DPD) [[cite:PUB00056209]].</p> <p>All described members of this enzyme family are composed of two homologous actin-like ATPase domains. A catalytic cleft is formed by the interface between these two domains, where the sugar substrate and ATP co-substrate bind.</p>

This description is obtained from EB-eye REST.

Associated GO terms

GO predictions are based solely on the InterPro-to-GO mappings published by EMBL-EBI, which are in turn based on the mapping of predicted domains to the InterPro dataset. The InterPro-to-GO mapping was last updated on , while the GO metadata was last updated on .

GO term Namespace Name Definition Relationships
GO:0005975
Biological process Carbohydrate metabolic process The chemical reactions and pathways involving carbohydrates, any of a group of organic compounds based of the general formula Cx(H2O)y. Includes the formation of carbohydrate derivatives by the addition of a carbohydrate residue to another molecule.
Subterm of
GO:0016773
Molecular function Phosphotransferase activity, alcohol group as acceptor Catalysis of the transfer of a phosphorus-containing group from one compound (donor) to an alcohol group (acceptor).
Subterm of

Associated Lotus transcripts 20

Transcript Name Description Predicted domains Domain count
Lj0g3v0267999.1
– PREDICTED: xylulose kinase-like [Glycine max] gi|356507959|ref|XP_003522730.1|
Domains
11
Lj1g3v2095960.2
– Xylulose kinase [Medicago truncatula] gi|357466769|ref|XP_003603669.1|
Domains
9
Lj3g3v2174780.1
– Glycerol kinase [Medicago truncatula] gi|357468137|ref|XP_003604353.1|
Domains
15
Lj3g3v2174790.1
–
Domains
10
Lj3g3v3376210.1
– PREDICTED: xylulose kinase-like [Glycine max] gi|356538722|ref|XP_003537850.1|
Domains
10
Lj3g3v3376210.3
– PREDICTED: xylulose kinase-like [Glycine max] gi|356538722|ref|XP_003537850.1|
Domains
6
Lj4g3v2080390.1
– PREDICTED: FGGY carbohydrate kinase domain-containing protein-like isoform X1 [Cicer arietinum] gi|502150178|ref|XP_004507826.1|
Domains
9
Lj4g3v2080390.2
– PREDICTED: FGGY carbohydrate kinase domain-containing protein-like isoform X2 [Cicer arietinum] gi|502150180|ref|XP_004507827.1|
Domains
6
LotjaGi1g1v0412400.1
– Xylulose kinase-like protein; TAIR: AT5G49650.1 xylulose kinase-2; Swiss-Prot: sp|Q5R830|XYLB_PONAB Xylulose kinase; TrEMBL-Plants: tr|I3SF17|I3SF17_LOTJA Uncharacterized protein; Found in the gene: LotjaGi1g1v0412400
Domains
13
LotjaGi3g1v0354200.1
– Glycerol kinase-like protein; TAIR: AT1G80460.1 Actin-like ATPase superfamily protein; Swiss-Prot: sp|Q9M8L4|GLPK_ARATH Glycerol kinase; TrEMBL-Plants: tr|G7JGV7|G7JGV7_MEDTR Glycerol kinase-like protein; Found in the gene: LotjaGi3g1v0354200
Domains
16
LotjaGi3g1v0513400.1
– Glycerol kinase; TAIR: AT2G21370.1 xylulose kinase-1; Swiss-Prot: sp|P27155|XYLB_STAXY Xylulose kinase; TrEMBL-Plants: tr|K7LP67|K7LP67_SOYBN Uncharacterized protein; Found in the gene: LotjaGi3g1v0513400
Domains
11
LotjaGi3g1v0513400.2
– Xylulose kinase-like protein; TAIR: AT2G21370.1 xylulose kinase-1; Swiss-Prot: sp|P27155|XYLB_STAXY Xylulose kinase; TrEMBL-Plants: tr|A0A0S3SDR1|A0A0S3SDR1_PHAAN Uncharacterized protein; Found in the gene: LotjaGi3g1v0513400
Domains
7
LotjaGi4g1v0298300.1
– Glycerol kinase; TAIR: AT4G30310.2 FGGY family of carbohydrate kinase; Swiss-Prot: sp|Q6DCD1|FGGY_XENLA FGGY carbohydrate kinase domain-containing protein; TrEMBL-Plants: tr|A0A1J7GZV6|A0A1J7GZV6_LUPAN Uncharacterized protein; Found in the gene: LotjaGi4g1v0298300
Domains
16
LotjaGi4g1v0298300.2
– Glycerol kinase; TAIR: AT4G30310.2 FGGY family of carbohydrate kinase; Swiss-Prot: sp|A2AJL3|FGGY_MOUSE FGGY carbohydrate kinase domain-containing protein; TrEMBL-Plants: tr|A0A151SRN4|A0A151SRN4_CAJCA FGGY carbohydrate kinase domain-containing protein; Found in the gene: LotjaGi4g1v0298300
Domains
7
LotjaGi4g1v0298300.3
– Glycerol kinase; TAIR: AT4G30310.2 FGGY family of carbohydrate kinase; Swiss-Prot: sp|A2AJL3|FGGY_MOUSE FGGY carbohydrate kinase domain-containing protein; TrEMBL-Plants: tr|A0A151SRN4|A0A151SRN4_CAJCA FGGY carbohydrate kinase domain-containing protein; Found in the gene: LotjaGi4g1v0298300
Domains
7
LotjaGi4g1v0298300.4
– Glycerol kinase; TAIR: AT4G30310.3 FGGY family of carbohydrate kinase; Swiss-Prot: sp|Q6DCD1|FGGY_XENLA FGGY carbohydrate kinase domain-containing protein; TrEMBL-Plants: tr|I1MST3|I1MST3_SOYBN Uncharacterized protein; Found in the gene: LotjaGi4g1v0298300
Domains
13
LotjaGi4g1v0298300.5
– Glycerol kinase; TAIR: AT4G30310.2 FGGY family of carbohydrate kinase; Swiss-Prot: sp|Q6DCD1|FGGY_XENLA FGGY carbohydrate kinase domain-containing protein; TrEMBL-Plants: tr|I1MST3|I1MST3_SOYBN Uncharacterized protein; Found in the gene: LotjaGi4g1v0298300
Domains
13
LotjaGi4g1v0298300.6
– Glycerol kinase; TAIR: AT4G30310.2 FGGY family of carbohydrate kinase; Swiss-Prot: sp|Q6DCD1|FGGY_XENLA FGGY carbohydrate kinase domain-containing protein; TrEMBL-Plants: tr|I1MST3|I1MST3_SOYBN Uncharacterized protein; Found in the gene: LotjaGi4g1v0298300
Domains
13
LotjaGi4g1v0298300.7
– Glycerol kinase; TAIR: AT4G30310.2 FGGY family of carbohydrate kinase; Swiss-Prot: sp|Q6DCD1|FGGY_XENLA FGGY carbohydrate kinase domain-containing protein; TrEMBL-Plants: tr|I1MST3|I1MST3_SOYBN Uncharacterized protein; Found in the gene: LotjaGi4g1v0298300
Domains
12
LotjaGi4g1v0298300.8
– Glycerol kinase; TAIR: AT4G30310.2 FGGY family of carbohydrate kinase; Swiss-Prot: sp|A2AJL3|FGGY_MOUSE FGGY carbohydrate kinase domain-containing protein; TrEMBL-Plants: tr|A0A151SRN4|A0A151SRN4_CAJCA FGGY carbohydrate kinase domain-containing protein; Found in the gene: LotjaGi4g1v0298300
Domains
7

Co-occuring domains 1

A list of co-occurring predicted domains within the L. japonicus gene space:

Predicted domain Source Observations Saturation (%)
SSF53067 SUPERFAMILY 1 5.00