Your browser is unable to support new features implemented in HTML5 and CSS3 to render this site as intended. Your experience may suffer from functionality degradation but the site should remain usable. We strongly recommend the latest version of Google Chrome, OS X Safari or Mozilla Firefox. As Safari is bundled with OS X, if you are unable to upgrade to a newer version of OS X, we recommend using an open source browser. Dismiss message
IPR006102 is a Glycoside hydrolase, family 2, immunoglobulin-like beta-sandwich.
<p>O-Glycosyl hydrolases ([ec:3.2.1.]) are a widespread group of enzymes that hydrolyse the glycosidic bond between two or more carbohydrates, or between a carbohydrate and a non-carbohydrate moiety. A classification system for glycosyl hydrolases, based on sequence similarity, has led to the definition of 85 different families [[cite:PUB00004870], [cite:PUB00005266]]. This classification is available on the CAZy (CArbohydrate-Active EnZymes) website.</p> <p>Glycoside hydrolase family 2 [cazy:GH2] comprises enzymes with several known activities: beta-galactosidase ([ec:3.2.1.23]); beta-mannosidase ([ec:3.2.1.25]); beta-glucuronidase ([ec:3.2.1.31]).</p> <p>These enzymes contain a conserved glutamic acid residue which has been shown [[cite:PUB00002709]], in Escherichia coli lacZ ([swissprot:P00722]), to be the general acid/base catalyst in the active site of the enzyme.</p> <p>This entry describes the immunoglobulin-like β-sandwich domain [[cite:PUB00004183]].</p>
This description is obtained from EB-eye REST.
GO predictions are based solely on the InterPro-to-GO mappings published by EMBL-EBI, which are in turn based on the mapping of predicted domains to the InterPro dataset. The InterPro-to-GO mapping was last updated on , while the GO metadata was last updated on .
| GO term | Namespace | Name | Definition | Relationships |
|---|---|---|---|---|
| Molecular function | Hydrolase activity, hydrolyzing O-glycosyl compounds | Catalysis of the hydrolysis of any O-glycosyl bond. | ||
| Biological process | Carbohydrate metabolic process | The chemical reactions and pathways involving carbohydrates, any of a group of organic compounds based of the general formula Cx(H2O)y. Includes the formation of carbohydrate derivatives by the addition of a carbohydrate residue to another molecule. |
| Transcript | Name | Description | Predicted domains | Domain count |
|---|---|---|---|---|
| – | PREDICTED: beta-galactosidase-like [Glycine max] gi|356548875|ref|XP_003542824.1| | 28 | ||
| – | PREDICTED: mannosylglycoprotein endo-beta-mannosidase-like [Cicer arietinum] gi|502113348|ref|XP_004494621.1| | 7 | ||
| – | PREDICTED: mannosylglycoprotein endo-beta-mannosidase-like [Cicer arietinum] gi|502113348|ref|XP_004494621.1| | 19 | ||
| – | PREDICTED: mannosylglycoprotein endo-beta-mannosidase-like [Glycine max] gi|356574941|ref|XP_003555601.1| | 19 | ||
| – | Beta-mannosidase, putative; TAIR: AT1G09010.1 glycoside hydrolase family 2 protein; Swiss-Prot: sp|Q5H7P5|EBM_LILLO Mannosylglycoprotein endo-beta-mannosidase; TrEMBL-Plants: tr|A0A151TW65|A0A151TW65_CAJCA Mannosylglycoprotein endo-beta-mannosidase; Found in the gene: LotjaGi1g1v0773700 | 21 | ||
| – | Beta-galactosidase; TAIR: AT3G54440.1 glycoside hydrolase family 2 protein; Swiss-Prot: sp|A5F5U6|BGAL_VIBC3 Beta-galactosidase; TrEMBL-Plants: tr|I1M0S4|I1M0S4_SOYBN Uncharacterized protein; Found in the gene: LotjaGi3g1v0318400 | 34 | ||
| – | Beta-mannosidase, putative; TAIR: AT1G09010.1 glycoside hydrolase family 2 protein; Swiss-Prot: sp|Q5H7P5|EBM_LILLO Mannosylglycoprotein endo-beta-mannosidase; TrEMBL-Plants: tr|I1NIZ2|I1NIZ2_SOYBN Uncharacterized protein; Found in the gene: LotjaGi5g1v0220600 | 21 | ||
| – | Beta-mannosidase, putative; TAIR: AT1G09010.1 glycoside hydrolase family 2 protein; Swiss-Prot: sp|Q5H7P5|EBM_LILLO Mannosylglycoprotein endo-beta-mannosidase; TrEMBL-Plants: tr|G7I838|G7I838_MEDTR Endo-beta-mannosidase-like mannosylglycoprotein; Found in the gene: LotjaGi5g1v0220600 | 19 |
A list of co-occurring predicted domains within the L. japonicus gene space:
| Predicted domain | Source | Observations | Saturation (%) |
|---|---|---|---|
| SSF51445 | SUPERFAMILY | 1 | 12.50 |