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IPR023232 is a Glycoside hydrolase, family 2, active site.
<p>O-Glycosyl hydrolases ([ec:3.2.1.]) are a widespread group of enzymes that hydrolyse the glycosidic bond between two or more carbohydrates, or between a carbohydrate and a non-carbohydrate moiety. A classification system for glycosyl hydrolases, based on sequence similarity, has led to the definition of 85 different families [[cite:PUB00004870], [cite:PUB00005266]]. This classification is available on the CAZy (CArbohydrate-Active EnZymes) website.</p> <p>Glycoside hydrolase 2 [cazy:GH2] comprises enzymes with several known activities; beta-galactosidase ([ec:3.2.1.23]); beta-mannosidase ([ec:3.2.1.25]); beta-glucuronidase ([ec:3.2.1.31]).</p> <p>These enzymes contain a conserved glutamic acid residue which has been shown [[cite:PUB00002709]], in Escherichia coli lacZ ([swissprot:P00722]), to be the general acid/base catalyst in the active site of the enzyme.</p> <p>This pattern signature contains the active site glutamic acid residue.</p>
This description is obtained from EB-eye REST.
| Transcript | Name | Description | Predicted domains | Domain count |
|---|---|---|---|---|
| – | PREDICTED: beta-galactosidase-like [Glycine max] gi|356548875|ref|XP_003542824.1| | 28 | ||
| – | PREDICTED: mannosylglycoprotein endo-beta-mannosidase-like [Cicer arietinum] gi|502113348|ref|XP_004494621.1| | 19 | ||
| – | PREDICTED: mannosylglycoprotein endo-beta-mannosidase-like [Glycine max] gi|356574941|ref|XP_003555601.1| | 19 | ||
| – | Beta-mannosidase, putative; TAIR: AT1G09010.1 glycoside hydrolase family 2 protein; Swiss-Prot: sp|Q5H7P5|EBM_LILLO Mannosylglycoprotein endo-beta-mannosidase; TrEMBL-Plants: tr|A0A151TW65|A0A151TW65_CAJCA Mannosylglycoprotein endo-beta-mannosidase; Found in the gene: LotjaGi1g1v0773700 | 21 | ||
| – | Beta-galactosidase; TAIR: AT3G54440.1 glycoside hydrolase family 2 protein; Swiss-Prot: sp|A5F5U6|BGAL_VIBC3 Beta-galactosidase; TrEMBL-Plants: tr|I1M0S4|I1M0S4_SOYBN Uncharacterized protein; Found in the gene: LotjaGi3g1v0318400 | 34 | ||
| – | Beta-mannosidase, putative; TAIR: AT1G09010.1 glycoside hydrolase family 2 protein; Swiss-Prot: sp|Q5H7P5|EBM_LILLO Mannosylglycoprotein endo-beta-mannosidase; TrEMBL-Plants: tr|I1NIZ2|I1NIZ2_SOYBN Uncharacterized protein; Found in the gene: LotjaGi5g1v0220600 | 21 | ||
| – | Beta-mannosidase, putative; TAIR: AT1G09010.1 glycoside hydrolase family 2 protein; Swiss-Prot: sp|Q5H7P5|EBM_LILLO Mannosylglycoprotein endo-beta-mannosidase; TrEMBL-Plants: tr|G7I838|G7I838_MEDTR Endo-beta-mannosidase-like mannosylglycoprotein; Found in the gene: LotjaGi5g1v0220600 | 19 |
A list of co-occurring predicted domains within the L. japonicus gene space:
| Predicted domain | Source | Observations | Saturation (%) |
|---|---|---|---|
| SSF51445 | SUPERFAMILY | 1 | 14.29 |