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IPR006828

Source: InterPro

Description

IPR006828 is a Association with the SNF1 complex (ASC) domain.

<p>Association with the SNF1 complex (ASC) domain is found in the Sip1/Sip2/Gal83/AMPKbeta subunits of the SNF1/AMP-activated protein kinase (AMPK) complex [[cite:PUB00072630]]. SNF1/AMPK are heterotrimeric enzymes composed of a catalytic alpha-subunit, a regulatory gamma-subunit and a regulatory/targeting beta-subunit [[cite:PUB00071601]]. Saccharomyces cerevisiae encodes three beta-subunit genes, Sip1, Sip2 and Gal83 [[cite:PUB00008604], [cite:PUB00071596]]. The beta-subunits function as target selective adaptors that recruit the catalytic kinase and regulator Snf4/gamma-subunits. The ASC domain is required for interaction with Snf4 [[cite:PUB00072630], [cite:PUB00071601]].</p> <p>The SNF1 kinase complex is required for transcriptional, metabolic, and developmental adaptations in response to glucose limitation [[cite:PUB00042779], [cite:PUB00071595]]. As glucose levels decrease, Snf1 is activated and promotes the use of alternative carbon sources.</p>

This description is obtained from EB-eye REST.

Associated GO terms

GO predictions are based solely on the InterPro-to-GO mappings published by EMBL-EBI, which are in turn based on the mapping of predicted domains to the InterPro dataset. The InterPro-to-GO mapping was last updated on , while the GO metadata was last updated on .

GO term Namespace Name Definition Relationships
GO:0005515
Molecular function Protein binding Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
Subterm of

Associated Lotus transcripts 8

Transcript Name Description Predicted domains Domain count
Lj0g3v0233389.1
– PREDICTED: SNF1-related protein kinase regulatory subunit beta-1-like [Glycine max] gi|356554272|ref|XP_003545472.1|
Domains
13
Lj3g3v3069060.1
– PREDICTED: SNF1-related protein kinase regulatory subunit beta-3-like [Glycine max] gi|356539424|ref|XP_003538198.1|
Domains
10
Lj6g3v1721620.1
– PREDICTED: SNF1-related protein kinase regulatory subunit beta-2-like [Glycine max] gi|356555761|ref|XP_003546198.1|
Domains
13
LotjaGi1g1v0055200.1
– SNF1-related protein kinase regulatory subunit beta-1; TAIR: AT5G21170.1 5'-AMP-activated protein kinase beta-2 subunit protein; Swiss-Prot: sp|Q84VQ1|KINB1_ARATH SNF1-related protein kinase regulatory subunit beta-1; TrEMBL-Plants: tr|A0A151U1N8|A0A151U1N8_CAJCA SNF1-related protein kinase regulatory subunit beta-1; Found in the gene: LotjaGi1g1v0055200
Domains
17
LotjaGi3g1v0487800.1
– SNF1-related protein kinase regulatory subunit beta-2; TAIR: AT2G28060.1 5'-AMP-activated protein kinase beta-2 subunit protein; Swiss-Prot: sp|Q9ZUU8|KINB3_ARATH SNF1-related protein kinase regulatory subunit beta-3; TrEMBL-Plants: tr|I3SNK1|I3SNK1_LOTJA Uncharacterized protein; Found in the gene: LotjaGi3g1v0487800
Domains
10
LotjaGi6g1v0283000.1
– SNF1-related protein kinase regulatory subunit beta-2; TAIR: AT4G16360.1 SNF1-related protein kinase regulatory subunit beta-2; Swiss-Prot: sp|Q9SCY5|KINB2_ARATH SNF1-related protein kinase regulatory subunit beta-2; TrEMBL-Plants: tr|I1MFR8|I1MFR8_SOYBN Uncharacterized protein; Found in the gene: LotjaGi6g1v0283000
Domains
17
LotjaGi6g1v0283000.2
– SNF1-related protein kinase regulatory subunit beta-2; TAIR: AT4G16360.1 SNF1-related protein kinase regulatory subunit beta-2; Swiss-Prot: sp|Q9SCY5|KINB2_ARATH SNF1-related protein kinase regulatory subunit beta-2; TrEMBL-Plants: tr|I1MFR8|I1MFR8_SOYBN Uncharacterized protein; Found in the gene: LotjaGi6g1v0283000
Domains
17
LotjaGi6g1v0283000.3
– SNF1-related protein kinase regulatory subunit beta-2; TAIR: AT4G16360.1 SNF1-related protein kinase regulatory subunit beta-2; Swiss-Prot: sp|Q9SCY5|KINB2_ARATH SNF1-related protein kinase regulatory subunit beta-2; TrEMBL-Plants: tr|I3S3S8|I3S3S8_LOTJA Uncharacterized protein; Found in the gene: LotjaGi6g1v0283000
Domains
16

Co-occuring domains 1

A list of co-occurring predicted domains within the L. japonicus gene space:

Predicted domain Source Observations Saturation (%)
cd02859 CDD 1 12.50