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IPR006849

Source: InterPro

Description

IPR006849 is a Elongator complex protein 1.

<p>Elongator complex protein 1 (also known as Iki3) is a component of the RNA polymerase II elongator complex, which is a major histone acetyltransferase component of the RNA polymerase II (RNAPII) holoenzyme. The eukaryotic elongator complex has been associated with many cellular activities, including transcriptional elongation [[cite:PUB00008616], [cite:PUB00019998]], but its main function is tRNA modification [[cite:PUB00043578], [cite:PUB00086635]]. It is required for the formation of 5-methoxy-carbonylmethyl (mcm5) and 5-carbamoylmethyl (ncm5) groups on uridine nucleosides present at the wobble position of many tRNAs [[cite:PUB00086633]].</p>

This description is obtained from EB-eye REST.

Associated GO terms

GO predictions are based solely on the InterPro-to-GO mappings published by EMBL-EBI, which are in turn based on the mapping of predicted domains to the InterPro dataset. The InterPro-to-GO mapping was last updated on , while the GO metadata was last updated on .

GO term Namespace Name Definition Relationships
GO:0002098
Biological process TRNA wobble uridine modification The process in which a uridine in position 34 of a tRNA is post-transcriptionally modified.
Subterm of
GO:0033588
Cellular component Elongator holoenzyme complex A heterohexameric protein complex that is involved in modification of wobble nucleosides in tRNA. The complex can associate physically with hyperphosphorylated RNA polymerase II; it contains two discrete heterotrimeric subcomplexes.
Subterm of

Associated Lotus transcripts 20

Transcript Name Description Predicted domains Domain count
Lj5g3v2263990.1
– PREDICTED: elongator complex protein 1-like isoform X2 [Cicer arietinum] gi|502121382|ref|XP_004497296.1|
Domains
8
LotjaGi1g1v0075200.1
– Elongator complex protein 1; TAIR: AT5G13680.1 IKI3 family protein; Swiss-Prot: sp|Q9FNA4|ELP1_ARATH Elongator complex protein 1; TrEMBL-Plants: tr|A0A072VSS4|A0A072VSS4_MEDTR Elongator complex protein 1; Found in the gene: LotjaGi1g1v0075200
Domains
8
LotjaGi1g1v0075200.3
– Elongator complex protein 1; TAIR: AT5G13680.1 IKI3 family protein; Swiss-Prot: sp|Q9FNA4|ELP1_ARATH Elongator complex protein 1; TrEMBL-Plants: tr|A0A072VRS1|A0A072VRS1_MEDTR Elongator complex protein 1; Found in the gene: LotjaGi1g1v0075200
Domains
7
LotjaGi1g1v0075200.4
– Elongator complex protein 1; TAIR: AT5G13680.1 IKI3 family protein; Swiss-Prot: sp|Q9FNA4|ELP1_ARATH Elongator complex protein 1; TrEMBL-Plants: tr|A0A072VSS4|A0A072VSS4_MEDTR Elongator complex protein 1; Found in the gene: LotjaGi1g1v0075200
Domains
8
LotjaGi5g1v0355700_LC.1
– Elongator complex protein 1; TAIR: AT5G13680.1 IKI3 family protein; Swiss-Prot: sp|Q9FNA4|ELP1_ARATH Elongator complex protein 1; TrEMBL-Plants: tr|A0A072VRS1|A0A072VRS1_MEDTR Elongator complex protein 1; Found in the gene: LotjaGi5g1v0355700_LC
Domains
7
LotjaGi5g1v0355700_LC.10
– Elongator complex protein 1; TAIR: AT5G13680.1 IKI3 family protein; Swiss-Prot: sp|Q9FNA4|ELP1_ARATH Elongator complex protein 1; TrEMBL-Plants: tr|A0A072VSS4|A0A072VSS4_MEDTR Elongator complex protein 1; Found in the gene: LotjaGi5g1v0355700_LC
Domains
7
LotjaGi5g1v0355700_LC.11
– Elongator complex protein 1; TAIR: AT5G13680.1 IKI3 family protein; Swiss-Prot: sp|Q9FNA4|ELP1_ARATH Elongator complex protein 1; TrEMBL-Plants: tr|A0A072VRS1|A0A072VRS1_MEDTR Elongator complex protein 1; Found in the gene: LotjaGi5g1v0355700_LC
Domains
2
LotjaGi5g1v0355700_LC.12
– Elongator complex protein 1; TAIR: AT5G13680.1 IKI3 family protein; Swiss-Prot: sp|Q9FNA4|ELP1_ARATH Elongator complex protein 1; TrEMBL-Plants: tr|A0A072VRS1|A0A072VRS1_MEDTR Elongator complex protein 1; Found in the gene: LotjaGi5g1v0355700_LC
Domains
8
LotjaGi5g1v0355700_LC.13
– Elongator complex protein 1; TAIR: AT5G13680.1 IKI3 family protein; Swiss-Prot: sp|Q9FNA4|ELP1_ARATH Elongator complex protein 1; TrEMBL-Plants: tr|V7BCU8|V7BCU8_PHAVU Elongator complex protein 1; Found in the gene: LotjaGi5g1v0355700_LC
Domains
2
LotjaGi5g1v0355700_LC.14
– Elongator complex protein 1; TAIR: AT5G13680.1 IKI3 family protein; Swiss-Prot: sp|Q9FNA4|ELP1_ARATH Elongator complex protein 1; TrEMBL-Plants: tr|A0A072VRS1|A0A072VRS1_MEDTR Elongator complex protein 1; Found in the gene: LotjaGi5g1v0355700_LC
Domains
7
LotjaGi5g1v0355700_LC.15
– Elongator complex protein 1; TAIR: AT5G13680.1 IKI3 family protein; Swiss-Prot: sp|Q9FNA4|ELP1_ARATH Elongator complex protein 1; TrEMBL-Plants: tr|A0A072VRS1|A0A072VRS1_MEDTR Elongator complex protein 1; Found in the gene: LotjaGi5g1v0355700_LC
Domains
7
LotjaGi5g1v0355700_LC.16
– Elongator complex protein 1; TAIR: AT5G13680.1 IKI3 family protein; Swiss-Prot: sp|Q9FNA4|ELP1_ARATH Elongator complex protein 1; TrEMBL-Plants: tr|A0A072VRS1|A0A072VRS1_MEDTR Elongator complex protein 1; Found in the gene: LotjaGi5g1v0355700_LC
Domains
8
LotjaGi5g1v0355700_LC.2
– Elongator complex protein 1; TAIR: AT5G13680.1 IKI3 family protein; Swiss-Prot: sp|Q9FNA4|ELP1_ARATH Elongator complex protein 1; TrEMBL-Plants: tr|A0A072VRS1|A0A072VRS1_MEDTR Elongator complex protein 1; Found in the gene: LotjaGi5g1v0355700_LC
Domains
5
LotjaGi5g1v0355700_LC.3
– Elongator complex protein 1; TAIR: AT5G13680.1 IKI3 family protein; Swiss-Prot: sp|Q9FNA4|ELP1_ARATH Elongator complex protein 1; TrEMBL-Plants: tr|A0A072VSS4|A0A072VSS4_MEDTR Elongator complex protein 1; Found in the gene: LotjaGi5g1v0355700_LC
Domains
4
LotjaGi5g1v0355700_LC.4
– Elongator complex protein 1; TAIR: AT5G13680.1 IKI3 family protein; Swiss-Prot: sp|Q9FNA4|ELP1_ARATH Elongator complex protein 1; TrEMBL-Plants: tr|A0A072VRS1|A0A072VRS1_MEDTR Elongator complex protein 1; Found in the gene: LotjaGi5g1v0355700_LC
Domains
7
LotjaGi5g1v0355700_LC.5
– Elongator complex protein 1; TAIR: AT5G13680.1 IKI3 family protein; Swiss-Prot: sp|Q9FNA4|ELP1_ARATH Elongator complex protein 1; TrEMBL-Plants: tr|A0A072VRS1|A0A072VRS1_MEDTR Elongator complex protein 1; Found in the gene: LotjaGi5g1v0355700_LC
Domains
3
LotjaGi5g1v0355700_LC.6
– Elongator complex protein 1; TAIR: AT5G13680.1 IKI3 family protein; Swiss-Prot: sp|Q9FNA4|ELP1_ARATH Elongator complex protein 1; TrEMBL-Plants: tr|A0A072VRS1|A0A072VRS1_MEDTR Elongator complex protein 1; Found in the gene: LotjaGi5g1v0355700_LC
Domains
7
LotjaGi5g1v0355700_LC.7
– Elongator complex protein 1; TAIR: AT5G13680.1 IKI3 family protein; Swiss-Prot: sp|Q9FNA4|ELP1_ARATH Elongator complex protein 1; TrEMBL-Plants: tr|A0A072VRS1|A0A072VRS1_MEDTR Elongator complex protein 1; Found in the gene: LotjaGi5g1v0355700_LC
Domains
2
LotjaGi5g1v0355700_LC.8
– Elongator complex protein 1; TAIR: AT5G13680.1 IKI3 family protein; Swiss-Prot: sp|Q9FNA4|ELP1_ARATH Elongator complex protein 1; TrEMBL-Plants: tr|A0A072VRS1|A0A072VRS1_MEDTR Elongator complex protein 1; Found in the gene: LotjaGi5g1v0355700_LC
Domains
8
LotjaGi5g1v0355700_LC.9
– Elongator complex protein 1; TAIR: AT5G13680.1 IKI3 family protein; Swiss-Prot: sp|Q9FNA4|ELP1_ARATH Elongator complex protein 1; TrEMBL-Plants: tr|V7BCU8|V7BCU8_PHAVU Elongator complex protein 1; Found in the gene: LotjaGi5g1v0355700_LC
Domains
2

Co-occuring domains 1

A list of co-occurring predicted domains within the L. japonicus gene space:

Predicted domain Source Observations Saturation (%)
PTHR12747 PANTHER 1 5.00