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IPR006910

Source: InterPro

Description

IPR006910 is a Rad21/Rec8-like protein, N-terminal.

<p>This domain represents a conserved N-terminal region found in eukaryotic cohesins of the Rad21, Rec8 and Scc1 families. Rad21/Rec8 like proteins mediate sister chromatid cohesion during mitosis and meiosis, as part of the cohesin complex [[cite:PUB00008651]]. Cohesion is necessary for homologous recombination (including double-strand break repair) and correct chromatid segregation. These proteins may also be involved in chromosome condensation. Dissociation at the metaphase to anaphase transition causes loss of cohesion and chromatid segregation [[cite:PUB00008652]].</p>

This description is obtained from EB-eye REST.

Associated GO terms

GO predictions are based solely on the InterPro-to-GO mappings published by EMBL-EBI, which are in turn based on the mapping of predicted domains to the InterPro dataset. The InterPro-to-GO mapping was last updated on , while the GO metadata was last updated on .

GO term Namespace Name Definition Relationships
GO:0005515
Molecular function Protein binding Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
Subterm of

Associated Lotus transcripts 7

Transcript Name Description Predicted domains Domain count
Lj1g3v2842390.1
– Double-strand-break repair protein rad21-like protein [Medicago truncatula] gi|357507871|ref|XP_003624224.1|
Domains
11
Lj1g3v2842390.2
– Double-strand-break repair protein rad21-like protein [Medicago truncatula] gi|357507871|ref|XP_003624224.1|
Domains
11
Lj1g3v3833930.1
– Double-strand-break repair protein rad21-like protein [Medicago truncatula] gi|357503841|ref|XP_003622209.1|
Domains
11
Lj3g3v0883700.1
– PREDICTED: sister chromatid cohesion 1 protein 3-like [Cicer arietinum] gi|502174620|ref|XP_004515558.1|
Domains
5
LotjaGi1g1v0488400.1
– Sister chromatid cohesion 1 protein; TAIR: AT5G16270.1 sister chromatid cohesion 1 protein 4; Swiss-Prot: sp|Q8W1Y0|SSC14_ARATH Sister chromatid cohesion 1 protein 4; TrEMBL-Plants: tr|A0A0B2S710|A0A0B2S710_GLYSO Sister chromatid cohesion 1 protein 3; Found in the gene: LotjaGi1g1v0488400
Domains
12
LotjaGi1g1v0620400.2
– Sister chromatid cohesion 1 protein; TAIR: AT5G40840.1 Rad21/Rec8-like family protein; Swiss-Prot: sp|Q9FQ20|SCC12_ARATH Sister chromatid cohesion 1 protein 2; TrEMBL-Plants: tr|G7L499|G7L499_MEDTR Sister chromatid cohesion 1 protein; Found in the gene: LotjaGi1g1v0620400
Domains
13
LotjaGi3g1v0125000.1
– Sister chromatid cohesion 1 protein; TAIR: AT3G59550.1 Rad21/Rec8-like family protein; Swiss-Prot: sp|Q9FQ19|SCC13_ARATH Sister chromatid cohesion 1 protein 3; TrEMBL-Plants: tr|A0A1J7GHV5|A0A1J7GHV5_LUPAN Uncharacterized protein; Found in the gene: LotjaGi3g1v0125000
Domains
10

Co-occuring domains 1

A list of co-occurring predicted domains within the L. japonicus gene space:

Predicted domain Source Observations Saturation (%)
mobidb-lite MobiDBLite 1 14.29