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IPR006955 is a Uso1/p115-like vesicle tethering protein, C-terminal.
<p>This domain identifies a group of proteins, which are described as: General vesicular transport factor, Transcytosis associate protein (TAP) and Vesicle docking protein. This myosin-shaped molecule consists of an N-terminal globular head region, a coiled-coil tail which mediates dimerisation, and a short C-terminal acidic region [[cite:PUB00008680]]. p115 tethers COP1 vesicles to the Golgi by binding the coiled coil proteins giantin (on the vesicles) and GM130 (on the Golgi), via its C-terminal acidic region. It is required for intercisternal transport in the Golgi stack. This domain is found in the acidic C-terminal region, which binds to the golgins giantin and GM130. p115 is thought to juxtapose two membranes by binding giantin with one acidic region, and GM130 with another [[cite:PUB00009038]].</p>
This description is obtained from EB-eye REST.
GO predictions are based solely on the InterPro-to-GO mappings published by EMBL-EBI, which are in turn based on the mapping of predicted domains to the InterPro dataset. The InterPro-to-GO mapping was last updated on , while the GO metadata was last updated on .
| GO term | Namespace | Name | Definition | Relationships |
|---|---|---|---|---|
| Biological process | Intracellular protein transport | The directed movement of proteins in a cell, including the movement of proteins between specific compartments or structures within a cell, such as organelles of a eukaryotic cell. | ||
| Biological process | Vesicle-mediated transport | A cellular transport process in which transported substances are moved in membrane-bounded vesicles; transported substances are enclosed in the vesicle lumen or located in the vesicle membrane. The process begins with a step that directs a substance to the forming vesicle, and includes vesicle budding and coating. Vesicles are then targeted to, and fuse with, an acceptor membrane. |
| Transcript | Name | Description | Predicted domains | Domain count |
|---|---|---|---|---|
| – | PREDICTED: golgin candidate 6-like [Cicer arietinum] gi|502090365|ref|XP_004489204.1| | 12 | ||
| – | Golgin candidate 6; TAIR: AT3G27530.1 golgin Putative 6; Swiss-Prot: sp|B0F9L4|GOGC6_ARATH Golgin candidate 6; TrEMBL-Plants: tr|A0A151RN78|A0A151RN78_CAJCA Uncharacterized protein; Found in the gene: LotjaGi2g1v0240200 | 12 | ||
| – | Golgin candidate 6; TAIR: AT3G27530.1 golgin Putative 6; Swiss-Prot: sp|B0F9L4|GOGC6_ARATH Golgin candidate 6; TrEMBL-Plants: tr|A0A151RN78|A0A151RN78_CAJCA Uncharacterized protein; Found in the gene: LotjaGi2g1v0240200 | 12 |
A list of co-occurring predicted domains within the L. japonicus gene space:
| Predicted domain | Source | Observations | Saturation (%) |
|---|---|---|---|
| mobidb-lite | MobiDBLite | 1 | 33.33 |