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IPR007533

Source: InterPro

Description

IPR007533 is a Cytochrome c oxidase assembly protein CtaG/Cox11.

<p>Cytochrome c oxidase assembly protein is essential for the assembly of functional cytochrome oxidase protein. In eukaryotes it is an integral protein of the mitochondrial inner membrane. Cox11 is essential for the insertion of Cu(I) ions to form the CuB site. This is essential for the stability of other structures in subunit I, for example haems a and a3, and the magnesium/manganese centre. Cox11 is probably only required in sub-stoichiometric amounts relative to the structural units [[cite:PUB00010096]]. The C-terminal region of the protein is known to form a dimer. Each monomer coordinates one Cu(I) ion via three conserved cysteine residues (111, 208 and 210) in Saccharomyces cerevisiae ([swissprot:P19516]). Met 224 is also thought to play a role in copper transfer or stabilising the copper site [[cite:PUB00010118]].</p>

This description is obtained from EB-eye REST.

Associated GO terms

GO predictions are based solely on the InterPro-to-GO mappings published by EMBL-EBI, which are in turn based on the mapping of predicted domains to the InterPro dataset. The InterPro-to-GO mapping was last updated on , while the GO metadata was last updated on .

GO term Namespace Name Definition Relationships
GO:0005507
Molecular function Copper ion binding Interacting selectively and non-covalently with copper (Cu) ions.
Subterm of

Associated Lotus transcripts 3

Transcript Name Description Predicted domains Domain count
Lj1g3v2143370.1
– PREDICTED: methyltransferase-like protein 17, mitochondrial-like [Glycine max] gi|356546324|ref|XP_003541577.1|
Domains
9
Lj1g3v2143370.2
– PREDICTED: methyltransferase-like protein 17, mitochondrial-like [Glycine max] gi|356546324|ref|XP_003541577.1|
Domains
9
LotjaGi6g1v0053300.1
– Cytochrome c oxidase assembly protein ctaG; TAIR: AT1G02410.1 cytochrome c oxidase assembly protein CtaG / Cox11 family; Swiss-Prot: sp|Q8GWR0|COX11_ARATH Cytochrome c oxidase assembly protein COX11, mitochondrial; TrEMBL-Plants: tr|I1MZH2|I1MZH2_SOYBN Uncharacterized protein; Found in the gene: LotjaGi6g1v0053300
Domains
12

Co-occuring domains 1

A list of co-occurring predicted domains within the L. japonicus gene space:

Predicted domain Source Observations Saturation (%)
TRANSMEMBRANE Phobius 1 33.33