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IPR008284

Source: InterPro

Description

IPR008284 is a Molybdenum cofactor biosynthesis, conserved site.

<p>Eukaryotic and prokaryotic molybdoenzymes require a molybdopterin cofactor (MoCF) for their activity. The biosynthesis of this cofactor involves a complex multistep enzymatic pathway. One of the eukaryotic proteins involved in this pathway is the Drosophila protein cinnamon [[cite:PUB00001935]] which is highly similar to gephyrin, a rat microtubule-associated protein which was thought to anchor the glycine receptor to subsynaptic microtubules.</p> <p>Cinnamon and gephyrin are evolutionary related, in their N-terminal half, to the Escherichia coli MoCF biosynthesis proteins mog/chlG and moaB/chlA2.</p>

This description is obtained from EB-eye REST.

Associated GO terms

GO predictions are based solely on the InterPro-to-GO mappings published by EMBL-EBI, which are in turn based on the mapping of predicted domains to the InterPro dataset. The InterPro-to-GO mapping was last updated on , while the GO metadata was last updated on .

GO term Namespace Name Definition Relationships
GO:0006777
Biological process Mo-molybdopterin cofactor biosynthetic process The chemical reactions and pathways resulting in the formation of the Mo-molybdopterin cofactor, essential for the catalytic activity of some enzymes. The cofactor consists of a mononuclear molybdenum (Mo) ion coordinated by one or two molybdopterin ligands.
Subterm of

Associated Lotus transcripts 2

Transcript Name Description Predicted domains Domain count
Lj2g3v2926350.3
– Molybdopterin biosynthesis protein CNX1-like [Glycine max] gi|363806738|ref|NP_001242529.1|
Domains
18
LotjaGi1g1v0059300.1
– Molybdopterin biosynthesis protein CNX1; TAIR: AT5G20990.1 molybdopterin biosynthesis CNX1 protein / molybdenum cofactor biosynthesis enzyme CNX1 (CNX1); Swiss-Prot: sp|Q39054|CNX1_ARATH Molybdopterin biosynthesis protein CNX1; TrEMBL-Plants: tr|A0A0B2S2T0|A0A0B2S2T0_GLYSO Molybdopterin biosynthesis protein CNX1; Found in the gene: LotjaGi1g1v0059300
Domains
25

Co-occuring domains 1

A list of co-occurring predicted domains within the L. japonicus gene space:

Predicted domain Source Observations Saturation (%)
cd00887 CDD 1 50.00