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IPR038987 is a Molybdopterin biosynthesis protein MoeA-like.
<p>Eukaryotic and prokaryotic molybdoenzymes require a molybdopterin cofactor (MoCF or Moco) for their activity. The biosynthesis of this cofactor involves a complex multistep enzymatic pathway. In bacteria, The final step in MoCF synthesis is the attachment of mononuclear Mo to MPT, a process that requires MoeA and which is enhanced by MogA in an Mg2 ATP-dependent manner [[cite:PUB00034758]].</p> <p>In eukaryotes, MogA and MoeA are fused into a single polypeptide chain, such as in Drosophila protein cinnamon [[cite:PUB00001935]]. The corresponding mammalian protein gephyrin has also been implicated in the anchoring of glycinergic receptors to the cytoskeleton at inhibitory synapses [[cite:PUB00088639], [cite:PUB00007738]].</p>
This description is obtained from EB-eye REST.
| Transcript | Name | Description | Predicted domains | Domain count |
|---|---|---|---|---|
| – | Molybdopterin biosynthesis protein CNX1; TAIR: AT5G20990.1 molybdopterin biosynthesis CNX1 protein / molybdenum cofactor biosynthesis enzyme CNX1 (CNX1); Swiss-Prot: sp|Q39054|CNX1_ARATH Molybdopterin biosynthesis protein CNX1; TrEMBL-Plants: tr|A0A0B2S2T0|A0A0B2S2T0_GLYSO Molybdopterin biosynthesis protein CNX1; Found in the gene: LotjaGi1g1v0059300 | 25 |
A list of co-occurring predicted domains within the L. japonicus gene space:
| Predicted domain | Source | Observations | Saturation (%) |
|---|---|---|---|
| cd00887 | CDD | 1 | 100.00 |