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IPR008409

Description

IPR008409 is a Pre-mRNA-splicing factor SPF27.

<p>Proteins in this family are involved in mRNA splicing [[cite:PUB00063011]]. This family includes pre-mRNA-splicing factor SPF27, SNT309 and Cwf7. In humans, SPF27 is a component of the PRP19-CDC5L complex that forms an integral part of the spliceosome and is required for activating pre-mRNA splicing. It may have a scaffolding role in the spliceosome assembly as it contacts all other components of the core complex [[cite:PUB00063012]].</p>

This description is obtained from EB-eye REST.

Associated GO terms

GO predictions are based solely on the InterPro-to-GO mappings published by EMBL-EBI, which are in turn based on the mapping of predicted domains to the InterPro dataset. The InterPro-to-GO mapping was last updated on , while the GO metadata was last updated on .

GO term Namespace Name Definition Relationships
Biological process MRNA processing Any process involved in the conversion of a primary mRNA transcript into one or more mature mRNA(s) prior to translation into polypeptide.

Associated Lotus transcripts 3

Transcript Name Description Predicted domains Domain count
PREDICTED: pre-mRNA-splicing factor SPF27 homolog [Cicer arietinum] gi|502128553|ref|XP_004500001.1| 5
PREDICTED: pre-mRNA-splicing factor SPF27 homolog [Cicer arietinum] gi|502128553|ref|XP_004500001.1| 5
Pre-mRNA-splicing factor SPF27; TAIR: AT3G18165.1 modifier of snc1,4; Swiss-Prot: sp|Q949S9|SPF27_ARATH Pre-mRNA-splicing factor SPF27 homolog; TrEMBL-Plants: tr|I3SET9|I3SET9_LOTJA Uncharacterized protein; Found in the gene: LotjaGi4g1v0462000 5

Co-occuring domains 1

A list of co-occurring predicted domains within the L. japonicus gene space:

Predicted domain Source Observations Saturation (%)
PTHR13296:SF0 PANTHER 1 33.33