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IPR010625 is a CHCH.
<p>A conserved motif was identified in the LOC118487 protein was called the CHCH motif. Alignment of this protein with related members showed the presence of three subgroups of proteins, which are called the S (Small), N (N-terminal extended) and C (C-terminal extended) subgroups. All three sub-groups of proteins have in common that they contain a predicted conserved [coiled coil 1]-[helix 1]-[coiled coil 2]-[helix 2] domain (CHCH domain). Within each helix of the CHCH domain, there are two cysteines present in a C-X9-C motif. The N-group contains an additional double helix domain, and each helix contains the C-X9-C motif. This family contains a number of characterised proteins: Cox19 protein -a nuclear gene of Saccharomyces cerevisiae, codes for an 11kDa protein (Cox19p) required for expression of cytochrome oxidase. Because cox19 mutants are able to synthesise the mitochondrial and nuclear gene products of cytochrome oxidase, Cox19p probably functions post-translationally during assembly of the enzyme. Cox19p is present in the cytoplasm and mitochondria, where it exists as a soluble intermembrane protein. This dual location is similar to what was previously reported for Cox17p, a low molecular weight copper protein thought to be required for maturation of the CuA centre of subunit 2 of cytochrome oxidase. Cox19p have four conserved potential metal ligands, these are three cysteines and one histidine. Mrp10 -belongs to the class of yeast mitochondrial ribosomal proteins that are essential for translation [[cite:PUB00010187]]. Eukaryotic NADH-ubiquinone oxidoreductase 19kDa (NDUFA8) subunit [[cite:PUB00011388]]. The CHCH domain was previously called DUF657 [[cite:PUB00019294]].</p>
This description is obtained from EB-eye REST.
| Transcript | Name | Description | Predicted domains | Domain count |
|---|---|---|---|---|
| – | PREDICTED: cytochrome c oxidase assembly protein COX19-like isoform X1 [Cicer arietinum] gi|502178641|ref|XP_004516302.1| | 3 | ||
| – | PREDICTED: mitochondrial intermembrane space import and assembly protein 40-like isoform X1 [Cicer arietinum] gi|502156432|ref|XP_004510471.1| | 4 | ||
| – | Cox19-like CHCH family protein [Arabidopsis thaliana] gi|15242455|ref|NP_196519.1| | 7 | ||
| – | Mitochondrial intermembrane space import and assembly protein 40; TAIR: AT5G23395.1 Cox19-like CHCH family protein; Swiss-Prot: sp|Q8GYJ4|MIA40_ARATH Mitochondrial intermembrane space import and assembly protein 40 homolog; TrEMBL-Plants: tr|I3SC92|I3SC92_LOTJA Uncharacterized protein; Found in the gene: LotjaGi3g1v0414400 | 6 | ||
| – | NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 8; TAIR: AT5G18800.1 Cox19-like CHCH family protein; Swiss-Prot: sp|Q8LGE7|NDA8B_ARATH NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 8-B; TrEMBL-Plants: tr|I3SL61|I3SL61_LOTJA Uncharacterized protein; Found in the gene: LotjaGi3g1v0431200 | 5 | ||
| – | NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 8; TAIR: AT5G18800.1 Cox19-like CHCH family protein; Swiss-Prot: sp|Q8LGE7|NDA8B_ARATH NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 8-B; TrEMBL-Plants: tr|I3SL61|I3SL61_LOTJA Uncharacterized protein; Found in the gene: LotjaGi3g1v0431200 | 5 | ||
| – | P8MTCP1; TAIR: AT5G09570.1 Cox19-like CHCH family protein; Swiss-Prot: sp|Q10307|YD52_SCHPO Uncharacterized protein C6C3.02c; TrEMBL-Plants: tr|S8C3U7|S8C3U7_9LAMI Uncharacterized protein; Found in the gene: LotjaGi4g1v0040400 | 8 | ||
| – | CHCH-like protein; TAIR: AT5G09570.1 Cox19-like CHCH family protein; Swiss-Prot: sp|Q10307|YD52_SCHPO Uncharacterized protein C6C3.02c; TrEMBL-Plants: tr|A0A0L9T900|A0A0L9T900_PHAAN Uncharacterized protein; Found in the gene: LotjaGi4g1v0040400 | 6 |
A list of co-occurring predicted domains within the L. japonicus gene space:
| Predicted domain | Source | Observations | Saturation (%) |
|---|---|---|---|
| SSF47072 | SUPERFAMILY | 1 | 12.50 |