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IPR010914

Source: InterPro

Description

IPR010914 is a RsgA GTPase domain.

<p>GTPases function as crucial molecular switches in a broad variety of biochemical processes. The majority of GTPases form a vast class of evolutionarily related proteins within the broader class of P-loop-containing ATPases. The P-loop GTPases share a conserved amino acid sequence G1-G3-G4 motif pattern (G2 is less well conserved) present in the GTPase domain. The Escherichia coli protein EngC (also known as RsgA) represents a protein family whose members are broadly conserved in bacteria and are indispensable for growth. The GTPase domain of RsgA is very similar to several P-loop GTPases, but differs in having a circular permutation of the GTPase structure described by a G4-G1-G3 pattern [[cite:PUB00013951]]. The RsgA-type GTPase domain is predominantly bacterial, with a probable acquisition by plants from chloroplasts [[cite:PUB00013952]].</p>

This description is obtained from EB-eye REST.

Associated GO terms

GO predictions are based solely on the InterPro-to-GO mappings published by EMBL-EBI, which are in turn based on the mapping of predicted domains to the InterPro dataset. The InterPro-to-GO mapping was last updated on , while the GO metadata was last updated on .

GO term Namespace Name Definition Relationships
GO:0003924
Molecular function GTPase activity Catalysis of the reaction: GTP + H2O = GDP + phosphate.
Subterm of
GO:0005525
Molecular function GTP binding Interacting selectively and non-covalently with GTP, guanosine triphosphate.
Subterm of

Associated Lotus transcripts 2

Transcript Name Description Predicted domains Domain count
Lj3g3v0950580.1
– Minichromosome maintenance family protein isoform 1 [Theobroma cacao] gi|508707992|gb|EOX99888.1|
Domains
18
LotjaGi3g1v0134500.1
– Small ribosomal subunit biogenesis GTPase RsgA; TAIR: AT1G67440.2 Minichromosome maintenance (MCM2/3/5) family protein; Swiss-Prot: sp|B0JW21|RSGA_MICAN Small ribosomal subunit biogenesis GTPase RsgA; TrEMBL-Plants: tr|A0A0L9T563|A0A0L9T563_PHAAN Uncharacterized protein; Found in the gene: LotjaGi3g1v0134500
Domains
18

Co-occuring domains 1

A list of co-occurring predicted domains within the L. japonicus gene space:

Predicted domain Source Observations Saturation (%)
mobidb-lite MobiDBLite 1 50.00