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IPR011564

Source: InterPro

Description

IPR011564 is a Telomeric single stranded DNA binding POT1/Cdc13.

<p>This domain binds single stranded telomeric DNA and adopts an OB fold [[cite:PUB00026858]]. It includes the proteins POT1 and Cdc13 which have been shown to regulate telomere length, replication and capping [[cite:PUB00053824], [cite:PUB00053825], [cite:PUB00053826]]. POT1 is one component of the shelterin complex that protects telomere-ends from attack by DNA-repair mechanisms [[cite:PUB00066756], [cite:PUB00066757]].</p>

This description is obtained from EB-eye REST.

Associated GO terms

GO predictions are based solely on the InterPro-to-GO mappings published by EMBL-EBI, which are in turn based on the mapping of predicted domains to the InterPro dataset. The InterPro-to-GO mapping was last updated on , while the GO metadata was last updated on .

GO term Namespace Name Definition Relationships
GO:0000723
Biological process Telomere maintenance Any process that contributes to the maintenance of proper telomeric length and structure by affecting and monitoring the activity of telomeric proteins, the length of telomeric DNA and the replication and repair of the DNA. These processes includes those that shorten, lengthen, replicate and repair the telomeric DNA sequences.
Subterm of
GO:0000784
Cellular component Nuclear chromosome, telomeric region The terminal region of a linear nuclear chromosome that includes the telomeric DNA repeats and associated proteins.
Subterm of
GO:0003677
Molecular function DNA binding Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid).
Subterm of

Associated Lotus transcripts 1

Transcript Name Description Predicted domains Domain count
Lj2g3v0661400.1
– PREDICTED: protection of telomeres protein 1b-like [Cicer arietinum] gi|502138042|ref|XP_004503267.1|
Domains
9

Co-occuring domains 1

A list of co-occurring predicted domains within the L. japonicus gene space:

Predicted domain Source Observations Saturation (%)
cd04497 CDD 1 100.00