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IPR012541 is a DBP10, C-terminal.
<p>This group of DEAD-box RNA helicases includes Dbp10 from fungi, DDX54 (also known as DP97) from mammals and RH29 from plants. DDX54 interacts in a hormone-dependent manner with nuclear receptors [[cite:PUB00101739], [cite:PUB00101740]]. It plays an important role in central nervous system myelination [[cite:PUB00078979]]. Dbp10 has a role in ribosome biogenesis [[cite:PUB00078980]]. RH29 is essential for the functional maturation of both male and female gametophytes [[cite:PUB00101741]].</p> <p>This entry represents the C-terminal domain.</p>
This description is obtained from EB-eye REST.
GO predictions are based solely on the InterPro-to-GO mappings published by EMBL-EBI, which are in turn based on the mapping of predicted domains to the InterPro dataset. The InterPro-to-GO mapping was last updated on , while the GO metadata was last updated on .
| GO term | Namespace | Name | Definition | Relationships |
|---|---|---|---|---|
| Molecular function | RNA binding | Interacting selectively and non-covalently with an RNA molecule or a portion thereof. | ||
| Molecular function | RNA helicase activity | Catalysis of the reaction: NTP + H2O = NDP + phosphate, to drive the unwinding of a RNA helix. | ||
| Molecular function | ATP binding | Interacting selectively and non-covalently with ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator. | ||
| Cellular component | Nucleus | A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent. |
| Transcript | Name | Description | Predicted domains | Domain count |
|---|---|---|---|---|
| – | Dead box ATP-dependent RNA helicase isoform 2 [Theobroma cacao] gi|508724625|gb|EOY16522.1| | 23 | ||
| – | Dead box ATP-dependent RNA helicase isoform 1 [Theobroma cacao] gi|508724624|gb|EOY16521.1| | 23 | ||
| – | Dead box ATP-dependent RNA helicase isoform 2 [Theobroma cacao] gi|508724625|gb|EOY16522.1| | 25 | ||
| – | Dead box ATP-dependent RNA helicase isoform 1 [Theobroma cacao] gi|508724624|gb|EOY16521.1| | 5 | ||
| – | ATP-dependent RNA helicase; TAIR: AT1G77030.1 putative DEAD-box ATP-dependent RNA helicase 29; Swiss-Prot: sp|O49289|RH29_ARATH Putative DEAD-box ATP-dependent RNA helicase 29; TrEMBL-Plants: tr|I1JJY8|I1JJY8_SOYBN Uncharacterized protein; Found in the gene: LotjaGi3g1v0052800 | 24 |
A list of co-occurring predicted domains within the L. japonicus gene space:
| Predicted domain | Source | Observations | Saturation (%) |
|---|---|---|---|
| mobidb-lite | MobiDBLite | 1 | 20.00 |