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IPR013120 is a Fatty acyl-coenzyme A reductase-like, NAD-binding domain.
<p>This entry represents the C-terminal NAD-binding region of the fatty acyl-coenzyme A reductases (FARs) from plants and animals. FARs catalyse the reduction of fatty acyl-CoA to fatty alcohols [[cite:PUB00095145], [cite:PUB00095146]].</p> <p>Proteins containing this domain also include funagal non-ribosomal peptide synthetases and non-reducing polyketide synthases. Non-ribosomal peptide synthetases are part of the gene cluster that mediates the biosynthesis of the lipopeptide antibiotics leucinostatins [[cite:PUB00095147]]. Non-reducing polyketide synthases are involved in the secondary metabolite biosynthesis [[cite:PUB00095129]].</p> <p>Proteins containing this domain also include L-2-aminoadipate reductase from yeast [[cite:PUB00013838]] and carboxylic acid reductase (Car) from bacteria [[cite:PUB00095148]].</p> <p>It is also found in Isonitrile lipopeptide synthase that is involved in the biosynthesis of a unique class of isonitrile lipopeptides that function as virulence factors in M.tuberculosis and have a role in metal acquisition [[cite:PUB00151132]].</p>
This description is obtained from EB-eye REST.
Transcript | Name | Description | Predicted domains | Domain count |
---|---|---|---|---|
– | PREDICTED: fatty acyl-CoA reductase 3-like [Glycine max] gi|356543580|ref|XP_003540238.1| | 11 | ||
– | Fatty acyl-CoA reductase [Medicago truncatula] gi|357491041|ref|XP_003615808.1| | 11 | ||
– | PREDICTED: fatty acyl-CoA reductase 2-like [Glycine max] gi|356503040|ref|XP_003520320.1| | 11 | ||
– | PREDICTED: fatty acyl-CoA reductase 3-like [Glycine max] gi|356543578|ref|XP_003540237.1| | 12 | ||
– | PREDICTED: fatty acyl-CoA reductase 3-like isoform 1 [Glycine max] gi|356550111|ref|XP_003543433.1| | 8 | ||
– | PREDICTED: fatty acyl-CoA reductase 3-like isoform 1 [Glycine max] gi|356542728|ref|XP_003539817.1| | 12 | ||
– | PREDICTED: fatty acyl-CoA reductase 3-like [Glycine max] gi|356539286|ref|XP_003538130.1| | 12 | ||
– | Fatty acyl-CoA reductase [Medicago truncatula] gi|357471749|ref|XP_003606159.1| | 8 | ||
– | Fatty acyl-CoA reductase [Medicago truncatula] gi|357471757|ref|XP_003606163.1| | 11 | ||
– | PREDICTED: fatty acyl-CoA reductase 3-like [Glycine max] gi|356541416|ref|XP_003539173.1| | 12 | ||
– | Fatty acyl-CoA reductase [Medicago truncatula] gi|357471757|ref|XP_003606163.1| | 11 | ||
– | PREDICTED: fatty acyl-CoA reductase 2-like [Glycine max] gi|356503040|ref|XP_003520320.1| | 11 | ||
– | Fatty acyl-CoA reductase; TAIR: AT4G33790.1 Jojoba acyl CoA reductase-related male sterility protein; Swiss-Prot: sp|Q93ZB9|FACR3_ARATH Fatty acyl-CoA reductase 3; TrEMBL-Plants: tr|A0A0B2QMM1|A0A0B2QMM1_GLYSO Fatty acyl-CoA reductase; Found in the gene: LotjaGi3g1v0175200 | 11 | ||
– | Fatty acyl-CoA reductase; TAIR: AT4G33790.1 Jojoba acyl CoA reductase-related male sterility protein; Swiss-Prot: sp|Q9XGY7|FAR_SIMCH Alcohol-forming fatty acyl-CoA reductase; TrEMBL-Plants: tr|K7M318|K7M318_SOYBN Fatty acyl-CoA reductase; Found in the gene: LotjaGi3g1v0175300 | 11 | ||
– | Fatty acyl-CoA reductase; TAIR: AT4G33790.1 Jojoba acyl CoA reductase-related male sterility protein; Swiss-Prot: sp|Q93ZB9|FACR3_ARATH Fatty acyl-CoA reductase 3; TrEMBL-Plants: tr|I1LRE5|I1LRE5_SOYBN Fatty acyl-CoA reductase; Found in the gene: LotjaGi3g1v0478900 | 11 | ||
– | Fatty acyl-CoA reductase; TAIR: AT4G33790.1 Jojoba acyl CoA reductase-related male sterility protein; Swiss-Prot: sp|Q93ZB9|FACR3_ARATH Fatty acyl-CoA reductase 3; TrEMBL-Plants: tr|I3T467|I3T467_LOTJA Fatty acyl-CoA reductase; Found in the gene: LotjaGi3g1v0479000 | 12 | ||
– | Fatty acyl-CoA reductase; TAIR: AT4G33790.1 Jojoba acyl CoA reductase-related male sterility protein; Swiss-Prot: sp|Q93ZB9|FACR3_ARATH Fatty acyl-CoA reductase 3; TrEMBL-Plants: tr|A0A1J7HZ71|A0A1J7HZ71_LUPAN Uncharacterized protein; Found in the gene: LotjaGi3g1v0479100 | 10 | ||
– | Fatty acyl-CoA reductase; TAIR: AT4G33790.1 Jojoba acyl CoA reductase-related male sterility protein; Swiss-Prot: sp|Q93ZB9|FACR3_ARATH Fatty acyl-CoA reductase 3; TrEMBL-Plants: tr|A0A1J7HZ71|A0A1J7HZ71_LUPAN Uncharacterized protein; Found in the gene: LotjaGi3g1v0479100 | 11 | ||
– | Fatty acyl-CoA reductase; TAIR: AT4G33790.1 Jojoba acyl CoA reductase-related male sterility protein; Swiss-Prot: sp|Q93ZB9|FACR3_ARATH Fatty acyl-CoA reductase 3; TrEMBL-Plants: tr|A0A1J7HZ71|A0A1J7HZ71_LUPAN Uncharacterized protein; Found in the gene: LotjaGi3g1v0479100 | 11 | ||
– | Fatty acyl-CoA reductase; TAIR: AT4G33790.1 Jojoba acyl CoA reductase-related male sterility protein; Swiss-Prot: sp|Q93ZB9|FACR3_ARATH Fatty acyl-CoA reductase 3; TrEMBL-Plants: tr|A0A1J7HZ71|A0A1J7HZ71_LUPAN Uncharacterized protein; Found in the gene: LotjaGi3g1v0479300 | 11 | ||
– | Fatty acyl-CoA reductase; TAIR: AT4G33790.1 Jojoba acyl CoA reductase-related male sterility protein; Swiss-Prot: sp|Q93ZB9|FACR3_ARATH Fatty acyl-CoA reductase 3; TrEMBL-Plants: tr|A0A1J7HZ71|A0A1J7HZ71_LUPAN Uncharacterized protein; Found in the gene: LotjaGi3g1v0479300 | 11 | ||
– | Fatty acyl-CoA reductase; TAIR: AT4G33790.1 Jojoba acyl CoA reductase-related male sterility protein; Swiss-Prot: sp|Q93ZB9|FACR3_ARATH Fatty acyl-CoA reductase 3; TrEMBL-Plants: tr|A0A1J7HZ71|A0A1J7HZ71_LUPAN Uncharacterized protein; Found in the gene: LotjaGi3g1v0479300 | 11 | ||
– | Cinnamyl alcohol dehydrogenase; TAIR: AT1G51410.1 NAD(P)-binding Rossmann-fold superfamily protein; Swiss-Prot: sp|Q9S9N9|CCR1_ARATH Cinnamoyl-CoA reductase 1; TrEMBL-Plants: tr|I3T4I3|I3T4I3_LOTJA Uncharacterized protein; Found in the gene: LotjaGi3g1v0536900 | 7 | ||
– | Fatty acyl-CoA reductase; TAIR: AT5G22500.1 fatty acid reductase 1; Swiss-Prot: sp|Q39152|FACR1_ARATH Fatty acyl-CoA reductase 1; TrEMBL-Plants: tr|A0A0L9V689|A0A0L9V689_PHAAN Fatty acyl-CoA reductase; Found in the gene: LotjaGi4g1v0129900 | 12 | ||
– | Fatty acyl-CoA reductase; TAIR: AT3G11980.1 Jojoba acyl CoA reductase-related male sterility protein; Swiss-Prot: sp|Q08891|FACR2_ARATH Fatty acyl-CoA reductase 2; TrEMBL-Plants: tr|A0A072VJJ5|A0A072VJJ5_MEDTR Fatty acyl-CoA reductase; Found in the gene: LotjaGi5g1v0115200 | 11 |
A list of co-occurring predicted domains within the L. japonicus gene space:
Predicted domain | Source | Observations | Saturation (%) |
---|---|---|---|
cd09071 | CDD | 1 | 4.00 |