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IPR013234

Source: InterPro

Description

IPR013234 is a PIGA, GPI anchor biosynthesis.

<p>This domain is found on phosphatidylinositol N-acetylglucosaminyltransferase proteins. These proteins are involved in GPI anchor biosynthesis and are associated with the disease paroxysmal nocturnal haemoglobinuria [[cite:PUB00017109]].</p>

This description is obtained from EB-eye REST.

Associated GO terms

GO predictions are based solely on the InterPro-to-GO mappings published by EMBL-EBI, which are in turn based on the mapping of predicted domains to the InterPro dataset. The InterPro-to-GO mapping was last updated on , while the GO metadata was last updated on .

GO term Namespace Name Definition Relationships
GO:0006506
Biological process GPI anchor biosynthetic process The chemical reactions and pathways resulting in the formation of a glycosylphosphatidylinositol (GPI) anchor that attaches some membrane proteins to the lipid bilayer of the cell membrane. The phosphatidylinositol group is linked via the C-6 hydroxyl residue of inositol to a carbohydrate chain which is itself linked to the protein via an ethanolamine phosphate group, its amino group forming an amide linkage with the C-terminal carboxyl of the protein. Some GPI anchors have variants on this canonical linkage.
Subterm of

Associated Lotus transcripts 7

Transcript Name Description Predicted domains Domain count
Lj3g3v1101750.1
– PREDICTED: phosphatidylinositol N-acetylglucosaminyltransferase subunit A-like [Glycine max] gi|356575054|ref|XP_003555657.1|
Domains
17
Lj3g3v1101750.2
– PREDICTED: phosphatidylinositol N-acetylglucosaminyltransferase subunit A-like [Glycine max] gi|356575054|ref|XP_003555657.1|
Domains
14
LotjaGi3g1v0166500.1
– Phosphatidylinositol N-acetylglucosaminyltransferase; TAIR: AT3G45100.1 UDP-Glycosyltransferase superfamily protein; Swiss-Prot: sp|Q94BX4|PIGA_ARATH Phosphatidylinositol N-acetylglucosaminyltransferase subunit A; TrEMBL-Plants: tr|K7N1Q9|K7N1Q9_SOYBN Uncharacterized protein; Found in the gene: LotjaGi3g1v0166500
Domains
11
LotjaGi3g1v0166500.2
– Phosphatidylinositol N-acetylglucosaminyltransferase; TAIR: AT3G45100.1 UDP-Glycosyltransferase superfamily protein; Swiss-Prot: sp|Q94BX4|PIGA_ARATH Phosphatidylinositol N-acetylglucosaminyltransferase subunit A; TrEMBL-Plants: tr|K7N1Q9|K7N1Q9_SOYBN Uncharacterized protein; Found in the gene: LotjaGi3g1v0166500
Domains
11
LotjaGi3g1v0166500.3
– Phosphatidylinositol N-acetylglucosaminyltransferase; TAIR: AT3G45100.1 UDP-Glycosyltransferase superfamily protein; Swiss-Prot: sp|Q94BX4|PIGA_ARATH Phosphatidylinositol N-acetylglucosaminyltransferase subunit A; TrEMBL-Plants: tr|K7N1R1|K7N1R1_SOYBN Uncharacterized protein; Found in the gene: LotjaGi3g1v0166500
Domains
9
LotjaGi3g1v0166500.4
– Glycogen synthase; TAIR: AT3G45100.1 UDP-Glycosyltransferase superfamily protein; Swiss-Prot: sp|Q94BX4|PIGA_ARATH Phosphatidylinositol N-acetylglucosaminyltransferase subunit A; TrEMBL-Plants: tr|K7N1R1|K7N1R1_SOYBN Uncharacterized protein; Found in the gene: LotjaGi3g1v0166500
Domains
9
LotjaGi3g1v0166500.5
– Phosphatidylinositol N-acetylglucosaminyltransferase; TAIR: AT3G45100.1 UDP-Glycosyltransferase superfamily protein; Swiss-Prot: sp|Q94BX4|PIGA_ARATH Phosphatidylinositol N-acetylglucosaminyltransferase subunit A; TrEMBL-Plants: tr|K7N1R1|K7N1R1_SOYBN Uncharacterized protein; Found in the gene: LotjaGi3g1v0166500
Domains
9

Co-occuring domains 1

A list of co-occurring predicted domains within the L. japonicus gene space:

Predicted domain Source Observations Saturation (%)
cd03796 CDD 1 14.29