Your browser is unable to support new features implemented in HTML5 and CSS3 to render this site as intended. Your experience may suffer from functionality degradation but the site should remain usable. We strongly recommend the latest version of Google Chrome, OS X Safari or Mozilla Firefox. As Safari is bundled with OS X, if you are unable to upgrade to a newer version of OS X, we recommend using an open source browser. Dismiss message
IPR013244 is a Sec39 domain.
<p>This entry represents a Sec39 domain, which can be found in yeast Sec39, human NBAS (neuroblastoma-amplified sequence) [[cite:PUB00072937]] and Arabidopsis MIP2 (MAG2-INTERACTING PROTEIN 2) [[cite:PUB00072936]]. They may be involved in Golgi-to-ER transport.</p> <p>Sec39 was originally identified as a protein involved in ER-Golgi transport in a large scale promoter shut down analysis of essential yeast genes [[cite:PUB00045128]]. A subsequent study found that Sec39p (Dsl3p) is required for Golgi-ER retrograde transport and is part of a very stable protein complex that also includes Dsl1p (in mammals ZW10), Tip20p (Rint-1) and the ER localized Q-SNARE proteins Ufe1p (syntaxin-18), Sec20p and Use1p [[cite:PUB00045128]]. This was confirmed in a genome-wide analysis of protein complexes [[cite:PUB00045129]].</p>
This description is obtained from EB-eye REST.
GO predictions are based solely on the InterPro-to-GO mappings published by EMBL-EBI, which are in turn based on the mapping of predicted domains to the InterPro dataset. The InterPro-to-GO mapping was last updated on , while the GO metadata was last updated on .
| GO term | Namespace | Name | Definition | Relationships |
|---|---|---|---|---|
| Biological process | Retrograde vesicle-mediated transport, Golgi to ER | The directed movement of substances from the Golgi back to the endoplasmic reticulum, mediated by vesicles bearing specific protein coats such as COPI or COG. |
| Transcript | Name | Description | Predicted domains | Domain count |
|---|---|---|---|---|
| – | Neuroblastoma-amplified sequence [Medicago truncatula] gi|357464029|ref|XP_003602296.1| | 4 | ||
| – | Neuroblastoma-amplified sequence [Medicago truncatula] gi|357464029|ref|XP_003602296.1| | 7 | ||
| – | Neuroblastoma-amplified sequence [Medicago truncatula] gi|357464029|ref|XP_003602296.1| | 6 | ||
| – | Neuroblastoma-amplified sequence [Medicago truncatula] gi|357464029|ref|XP_003602296.1| | 4 | ||
| – | Neuroblastoma-amplified sequence; TAIR: AT5G24350.1 neuroblastoma-amplified sequence protein; Swiss-Prot: sp|Q9FIN7|MIP2_ARATH MAG2-interacting protein 2; TrEMBL-Plants: tr|I1KAW5|I1KAW5_SOYBN Uncharacterized protein; Found in the gene: LotjaGi1g1v0291300 | 6 | ||
| – | Neuroblastoma-amplified sequence; TAIR: AT5G24350.1 neuroblastoma-amplified sequence protein; Swiss-Prot: sp|Q9FIN7|MIP2_ARATH MAG2-interacting protein 2; TrEMBL-Plants: tr|I1KAW5|I1KAW5_SOYBN Uncharacterized protein; Found in the gene: LotjaGi1g1v0291300 | 6 | ||
| – | Neuroblastoma-amplified sequence; TAIR: AT5G24350.1 neuroblastoma-amplified sequence protein; Swiss-Prot: sp|Q9FIN7|MIP2_ARATH MAG2-interacting protein 2; TrEMBL-Plants: tr|K7KLV4|K7KLV4_SOYBN Uncharacterized protein; Found in the gene: LotjaGi1g1v0291300 | 3 | ||
| – | Neuroblastoma-amplified sequence; TAIR: AT5G24350.1 neuroblastoma-amplified sequence protein; Swiss-Prot: sp|Q9FIN7|MIP2_ARATH MAG2-interacting protein 2; TrEMBL-Plants: tr|A0A0R0KIZ5|A0A0R0KIZ5_SOYBN Uncharacterized protein; Found in the gene: LotjaGi1g1v0291300 | 3 | ||
| – | Neuroblastoma-amplified sequence; TAIR: AT5G24350.1 neuroblastoma-amplified sequence protein; Swiss-Prot: sp|Q9FIN7|MIP2_ARATH MAG2-interacting protein 2; TrEMBL-Plants: tr|K7KLV4|K7KLV4_SOYBN Uncharacterized protein; Found in the gene: LotjaGi1g1v0291300 | 3 |
A list of co-occurring predicted domains within the L. japonicus gene space:
| Predicted domain | Source | Observations | Saturation (%) |
|---|---|---|---|
| PTHR15922 | PANTHER | 1 | 11.11 |