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IPR013922 is a Cyclin PHO80-like.
<p>Cyclins are eukaryotic proteins that play an active role in controlling nuclear cell division cycles [[cite:PUB00014103]], and regulate cyclin dependent kinases (CDKs). Cyclins, together with the p34 (cdc2) or cdk2 kinases, form the Maturation Promoting Factor (MPF). There are two main groups of cyclins, G1/S cyclins, which are essential for the control of the cell cycle at the G1/S (start) transition, and G2/M cyclins, which are essential for the control of the cell cycle at the G2/M (mitosis) transition. G2/M cyclins accumulate steadily during G2 and are abruptly destroyed as cells exit from mitosis (at the end of the M-phase). In most species, there are multiple forms of G1 and G2 cyclins. For example, in vertebrates, there are two G2 cyclins, A and B, and at least three G1 cyclins, C, D, and E.</p> <p>Cyclin homologues have been found in various viruses, including Saimiriine herpesvirus 2 (Herpesvirus saimiri) and Human herpesvirus 8 (HHV-8) (Kaposi's sarcoma-associated herpesvirus). These viral homologues differ from their cellular counterparts in that the viral proteins have gained new functions and eliminated others to harness the cell and benefit the virus [[cite:PUB00014101]].</p> <p>This entry includes cyclin PHO80 and other cyclins that partner with the cyclin-dependent kinase (CDK) PHO85. The PHO80/PHO85 cyclin-cdk complex is used for a regulatory process other than cell-cycle control [[cite:PUB00033650]]. This entry also includes other PHO80-like cyclins that are involved in the cell-cycle control. They belong to the P/U family and interact preferentially with CDKA1 [[cite:PUB00055074]].</p>
This description is obtained from EB-eye REST.
GO predictions are based solely on the InterPro-to-GO mappings published by EMBL-EBI, which are in turn based on the mapping of predicted domains to the InterPro dataset. The InterPro-to-GO mapping was last updated on , while the GO metadata was last updated on .
| GO term | Namespace | Name | Definition | Relationships |
|---|---|---|---|---|
| Biological process | Regulation of cyclin-dependent protein serine/threonine kinase activity | Any process that modulates the frequency, rate or extent of cyclin-dependent protein serine/threonine kinase activity. | ||
| Molecular function | Protein kinase binding | Interacting selectively and non-covalently with a protein kinase, any enzyme that catalyzes the transfer of a phosphate group, usually from ATP, to a protein substrate. |
| Transcript | Name | Description | Predicted domains | Domain count |
|---|---|---|---|---|
| – | PREDICTED: cyclin-U2-2-like [Cicer arietinum] gi|502167736|ref|XP_004514236.1| | 9 | ||
| – | PREDICTED: cyclin-U2-1-like [Glycine max] gi|356541328|ref|XP_003539130.1| | 4 | ||
| – | PREDICTED: cyclin-U4-1-like [Glycine max] gi|356568557|ref|XP_003552477.1| | 9 | ||
| – | PREDICTED: cyclin-U2-2-like [Cicer arietinum] gi|502167736|ref|XP_004514236.1| | 9 | ||
| – | PREDICTED: cyclin-P3-1-like [Cicer arietinum] gi|502109535|ref|XP_004493668.1| | 8 | ||
| – | PREDICTED: cyclin-U4-1-like [Glycine max] gi|356520736|ref|XP_003529016.1| | 9 | ||
| – | PREDICTED: cyclin-U1-1-like [Glycine max] gi|356543744|ref|XP_003540320.1| | 10 | ||
| – | Cyclin family protein; TAIR: AT2G44740.1 cyclin p4;1; Swiss-Prot: sp|O80513|CCU41_ARATH Cyclin-U4-1; TrEMBL-Plants: tr|I3SNV3|I3SNV3_LOTJA Uncharacterized protein; Found in the gene: LotjaGi1g1v0492000 | 9 | ||
| – | Cyclin family protein; TAIR: AT2G44740.1 cyclin p4;1; Swiss-Prot: sp|O80513|CCU41_ARATH Cyclin-U4-1; TrEMBL-Plants: tr|I3SNV3|I3SNV3_LOTJA Uncharacterized protein; Found in the gene: LotjaGi1g1v0492000 | 9 | ||
| – | Cyclin family protein; TAIR: AT3G60550.1 cyclin p3;2; Swiss-Prot: sp|Q9M205|CCU22_ARATH Cyclin-U2-2; TrEMBL-Plants: tr|A0A0B2PDT8|A0A0B2PDT8_GLYSO Cyclin-U2-1; Found in the gene: LotjaGi1g1v0601100 | 9 | ||
| – | Cyclin family protein; TAIR: AT3G60550.1 cyclin p3;2; Swiss-Prot: sp|Q9M205|CCU22_ARATH Cyclin-U2-2; TrEMBL-Plants: tr|B7FJB0|B7FJB0_MEDTR Uncharacterized protein; Found in the gene: LotjaGi1g1v0601100 | 5 | ||
| – | Cyclin family protein; TAIR: AT3G60550.1 cyclin p3;2; Swiss-Prot: sp|Q9M205|CCU22_ARATH Cyclin-U2-2; TrEMBL-Plants: tr|A0A0B2PDT8|A0A0B2PDT8_GLYSO Cyclin-U2-1; Found in the gene: LotjaGi1g1v0601100 | 9 | ||
| – | Cyclin family protein; TAIR: AT3G63120.1 cyclin p1;1; Swiss-Prot: sp|Q75HV0|CCP31_ORYSJ Cyclin-P3-1; TrEMBL-Plants: tr|I3SVB5|I3SVB5_LOTJA Uncharacterized protein; Found in the gene: LotjaGi1g1v0727600 | 9 | ||
| – | Cyclin family protein; TAIR: AT3G63120.1 cyclin p1;1; Swiss-Prot: sp|Q75HV0|CCP31_ORYSJ Cyclin-P3-1; TrEMBL-Plants: tr|I3SVB5|I3SVB5_LOTJA Uncharacterized protein; Found in the gene: LotjaGi1g1v0727600 | 9 | ||
| – | Cyclin family protein; TAIR: AT3G63120.1 cyclin p1;1; Swiss-Prot: sp|Q75HV0|CCP31_ORYSJ Cyclin-P3-1; TrEMBL-Plants: tr|I3SVB5|I3SVB5_LOTJA Uncharacterized protein; Found in the gene: LotjaGi1g1v0727600 | 9 | ||
| – | Cyclin family protein; TAIR: AT2G44740.1 cyclin p4;1; Swiss-Prot: sp|O80513|CCU41_ARATH Cyclin-U4-1; TrEMBL-Plants: tr|A0A151RAV1|A0A151RAV1_CAJCA Cyclin-U4-1; Found in the gene: LotjaGi3g1v0069300 | 9 | ||
| – | Cyclin family protein; TAIR: AT2G44740.1 cyclin p4;1; Swiss-Prot: sp|O80513|CCU41_ARATH Cyclin-U4-1; TrEMBL-Plants: tr|A0A151RAV1|A0A151RAV1_CAJCA Cyclin-U4-1; Found in the gene: LotjaGi3g1v0069300 | 9 | ||
| – | Cyclin family protein; TAIR: AT2G44740.1 cyclin p4;1; Swiss-Prot: sp|O80513|CCU41_ARATH Cyclin-U4-1; TrEMBL-Plants: tr|A0A151RAV1|A0A151RAV1_CAJCA Cyclin-U4-1; Found in the gene: LotjaGi3g1v0069300 | 9 | ||
| – | Cyclin family protein; TAIR: AT3G21870.1 cyclin p2;1; Swiss-Prot: sp|Q9LJ45|CCU11_ARATH Cyclin-U1-1; TrEMBL-Plants: tr|I1LU79|I1LU79_SOYBN Uncharacterized protein; Found in the gene: LotjaGi3g1v0191500 | 10 | ||
| – | Cyclin family protein; TAIR: AT2G45080.1 cyclin p3;1; Swiss-Prot: sp|Q9SHD3|CCU21_ARATH Cyclin-U2-1; TrEMBL-Plants: tr|A0A0L9VR13|A0A0L9VR13_PHAAN Uncharacterized protein; Found in the gene: LotjaGi3g1v0204600 | 9 | ||
| – | Cyclin family protein; TAIR: AT2G45080.1 cyclin p3;1; Swiss-Prot: sp|Q9SHD3|CCU21_ARATH Cyclin-U2-1; TrEMBL-Plants: tr|A0A0L9VR13|A0A0L9VR13_PHAAN Uncharacterized protein; Found in the gene: LotjaGi3g1v0204600 | 5 | ||
| – | Cyclin family protein; TAIR: AT2G45080.1 cyclin p3;1; Swiss-Prot: sp|Q9SHD3|CCU21_ARATH Cyclin-U2-1; TrEMBL-Plants: tr|A0A0L9VR13|A0A0L9VR13_PHAAN Uncharacterized protein; Found in the gene: LotjaGi3g1v0204600 | 10 |
A list of co-occurring predicted domains within the L. japonicus gene space:
| Predicted domain | Source | Observations | Saturation (%) |
|---|---|---|---|
| SignalP-TM | SignalP_GRAM_NEGATIVE | 1 | 4.55 |