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IPR014551 is a Beta-glucosidase GBA2-type.
<p>Non-lysosomal glucosylceramidase, also known as beta-glucosidase 2 (GBA2) is an enzyme involved in an alternative catabolic pathway of glucosylceramide [[cite:PUB00044658]]. GBA2, has been characterised as a bile acid beta-glucosidase [[cite:PUB00027918]]. It is unrelated to other known glucosidases, but it has homologues among bacteria and archaea [[cite:PUB00073615]].</p>
This description is obtained from EB-eye REST.
GO predictions are based solely on the InterPro-to-GO mappings published by EMBL-EBI, which are in turn based on the mapping of predicted domains to the InterPro dataset. The InterPro-to-GO mapping was last updated on , while the GO metadata was last updated on .
GO term | Namespace | Name | Definition | Relationships |
---|---|---|---|---|
Molecular function | Glucosylceramidase activity | Catalysis of the reaction: D-glucosyl-N-acylsphingosine + H2O = D-glucose + N-acylsphingosine. | ||
Biological process | Glucosylceramide catabolic process | The chemical reactions and pathways resulting in the breakdown of glucosylceramides, any compound formed by the replacement of the glycosidic hydroxyl group of a cyclic form of glucose by a ceramide group. | ||
Cellular component | Membrane | A lipid bilayer along with all the proteins and protein complexes embedded in it an attached to it. |
Transcript | Name | Description | Predicted domains | Domain count |
---|---|---|---|---|
– | Non-lysosomal glucosylceramidase [Medicago truncatula] gi|357440847|ref|XP_003590701.1| | 12 | ||
– | Non-lysosomal glucosylceramidase; TAIR: AT5G49900.1 Beta-glucosidase, GBA2 type family protein; Swiss-Prot: sp|Q69ZF3|GBA2_MOUSE Non-lysosomal glucosylceramidase; TrEMBL-Plants: tr|A0A072UUL4|A0A072UUL4_MEDTR Non-lysosomal glucosylceramidase; Found in the gene: LotjaGi4g1v0001000 | 13 | ||
– | Non-lysosomal glucosylceramidase; TAIR: AT5G49900.1 Beta-glucosidase, GBA2 type family protein; Swiss-Prot: sp|Q69ZF3|GBA2_MOUSE Non-lysosomal glucosylceramidase; TrEMBL-Plants: tr|A0A072UUL4|A0A072UUL4_MEDTR Non-lysosomal glucosylceramidase; Found in the gene: LotjaGi4g1v0001000 | 13 | ||
– | Non-lysosomal glucosylceramidase; TAIR: AT5G49900.1 Beta-glucosidase, GBA2 type family protein; Swiss-Prot: sp|Q69ZF3|GBA2_MOUSE Non-lysosomal glucosylceramidase; TrEMBL-Plants: tr|A0A072UUL4|A0A072UUL4_MEDTR Non-lysosomal glucosylceramidase; Found in the gene: LotjaGi4g1v0001000 | 13 | ||
– | Non-lysosomal glucosylceramidase; TAIR: AT3G24180.1 Beta-glucosidase, GBA2 type family protein; Swiss-Prot: sp|Q69ZF3|GBA2_MOUSE Non-lysosomal glucosylceramidase; TrEMBL-Plants: tr|A0A0S3SPA3|A0A0S3SPA3_PHAAN Non-lysosomal glucosylceramidase; Found in the gene: LotjaGi5g1v0163400 | 13 | ||
– | Non-lysosomal glucosylceramidase; TAIR: AT3G24180.1 Beta-glucosidase, GBA2 type family protein; Swiss-Prot: sp|Q69ZF3|GBA2_MOUSE Non-lysosomal glucosylceramidase; TrEMBL-Plants: tr|A0A072VX24|A0A072VX24_MEDTR Non-lysosomal glucosylceramidase; Found in the gene: LotjaGi5g1v0163400 | 13 | ||
– | Non-lysosomal glucosylceramidase; TAIR: AT3G24180.1 Beta-glucosidase, GBA2 type family protein; Swiss-Prot: sp|Q69ZF3|GBA2_MOUSE Non-lysosomal glucosylceramidase; TrEMBL-Plants: tr|A0A0S3SPA3|A0A0S3SPA3_PHAAN Non-lysosomal glucosylceramidase; Found in the gene: LotjaGi5g1v0163400 | 12 | ||
– | Non-lysosomal glucosylceramidase; TAIR: AT3G24180.1 Beta-glucosidase, GBA2 type family protein; Swiss-Prot: sp|Q69ZF3|GBA2_MOUSE Non-lysosomal glucosylceramidase; TrEMBL-Plants: tr|A0A0S3SPA3|A0A0S3SPA3_PHAAN Non-lysosomal glucosylceramidase; Found in the gene: LotjaGi5g1v0163400 | 14 | ||
– | Non-lysosomal glucosylceramidase; TAIR: AT3G24180.1 Beta-glucosidase, GBA2 type family protein; Swiss-Prot: sp|Q69ZF3|GBA2_MOUSE Non-lysosomal glucosylceramidase; TrEMBL-Plants: tr|A0A0S3SPA3|A0A0S3SPA3_PHAAN Non-lysosomal glucosylceramidase; Found in the gene: LotjaGi5g1v0163400 | 13 | ||
– | Non-lysosomal glucosylceramidase; TAIR: AT3G24180.1 Beta-glucosidase, GBA2 type family protein; Swiss-Prot: sp|Q69ZF3|GBA2_MOUSE Non-lysosomal glucosylceramidase; TrEMBL-Plants: tr|A0A0S3SPA3|A0A0S3SPA3_PHAAN Non-lysosomal glucosylceramidase; Found in the gene: LotjaGi5g1v0163400 | 13 |
A list of co-occurring predicted domains within the L. japonicus gene space:
Predicted domain | Source | Observations | Saturation (%) |
---|---|---|---|
mobidb-lite | MobiDBLite | 1 | 10.00 |