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IPR015342

Description

IPR015342 is a Peroxisomal ATPase PEX1, N-terminal C-lobe.

<p>The N-terminal domain of PEX1 adopts a double ψ β-barrel fold, similar in structure to the Cdc48 N-terminal domain. It has been suggested that this domain may be involved in interactions with ubiquitin, ubiquitin-like protein modifiers, or ubiquitin-like domains, such as Ubx. Furthermore, the domain may possess a putative adaptor or substrate binding site, allowing for peroxisomal biogenesis, membrane fusion and protein translocation [[cite:PUB00035447]]. This domain can be subdivided in N- and C-lobes. This entry represents the C-lobe.</p>

This description is obtained from EB-eye REST.

Associated GO terms

GO predictions are based solely on the InterPro-to-GO mappings published by EMBL-EBI, which are in turn based on the mapping of predicted domains to the InterPro dataset. The InterPro-to-GO mapping was last updated on , while the GO metadata was last updated on .

GO term Namespace Name Definition Relationships
Molecular function ATP binding Interacting selectively and non-covalently with ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.
Cellular component Peroxisome A small organelle enclosed by a single membrane, and found in most eukaryotic cells. Contains peroxidases and other enzymes involved in a variety of metabolic processes including free radical detoxification, lipid catabolism and biosynthesis, and hydrogen peroxide metabolism.
Biological process Peroxisome organization A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a peroxisome. A peroxisome is a small, membrane-bounded organelle that uses dioxygen (O2) to oxidize organic molecules.

Associated Lotus transcripts 3

Transcript Name Description Predicted domains Domain count
PREDICTED: peroxisome biogenesis protein 1-like [Glycine max] gi|356521604|ref|XP_003529444.1| 10
PREDICTED: peroxisome biogenesis protein 1-like [Glycine max] gi|356521604|ref|XP_003529444.1| 19
ATP-dependent zinc metalloprotease FtsH 1; TAIR: AT5G08470.1 peroxisome 1; Swiss-Prot: sp|Q9FNP1|PEX1_ARATH Peroxisome biogenesis protein 1; TrEMBL-Plants: tr|I1KMB2|I1KMB2_SOYBN Uncharacterized protein; Found in the gene: LotjaGi4g1v0086200 23

Co-occuring domains 1

A list of co-occurring predicted domains within the L. japonicus gene space:

Predicted domain Source Observations Saturation (%)
cd00009 CDD 1 33.33