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IPR016206

Source: InterPro

Description

IPR016206 is a Ketol-acid reductoisomerase, plant.

<p>Ketol-acid reductoisomerases (KARI) catalyses two steps in the biosynthesis of branched-chain amino acids. The reaction involves an Mg2+ dependent alkyl migration followed by an NADPH-dependent reduction of the 2-keto group. There are two groups of KARI enzymes: class I is a short form found in fungi and most bacteria, and class II is a long form found in plants and certain bacteria (although their sequences differ) [[cite:PUB00034453], [cite:PUB00036035]]. However, there has also been a long form found in certain bacteria, but these differ from class II sequences found in plants.</p> <p>This group represents a ketol-acid reductoisomerase, plant type.</p>

This description is obtained from EB-eye REST.

Associated GO terms

GO predictions are based solely on the InterPro-to-GO mappings published by EMBL-EBI, which are in turn based on the mapping of predicted domains to the InterPro dataset. The InterPro-to-GO mapping was last updated on , while the GO metadata was last updated on .

GO term Namespace Name Definition Relationships
GO:0004455
Molecular function Ketol-acid reductoisomerase activity Catalysis of the reaction: (R)-2,3-dihydroxy-3-methylbutanoate + NADP+ = (S)-2-hydroxy-2-methyl-3-oxobutanoate + NADPH + H+.
Subterm of
GO:0055114
Biological process Oxidation-reduction process A metabolic process that results in the removal or addition of one or more electrons to or from a substance, with or without the concomitant removal or addition of a proton or protons.
Subterm of

Associated Lotus transcripts 1

Transcript Name Description Predicted domains Domain count
LotjaGi3g1v0247900.1
– Ketol-acid reductoisomerase (NADP(+)); TAIR: AT3G58610.1 ketol-acid reductoisomerase; Swiss-Prot: sp|O82043|ILV5_PEA Ketol-acid reductoisomerase, chloroplastic; TrEMBL-Plants: tr|G7JCK0|G7JCK0_MEDTR Ketol-acid reductoisomerase; Found in the gene: LotjaGi3g1v0247900
Domains
24

Co-occuring domains 1

A list of co-occurring predicted domains within the L. japonicus gene space:

Predicted domain Source Observations Saturation (%)
SignalP-TM SignalP_GRAM_NEGATIVE 1 100.00