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IPR016721 is a Bet3 family.
<p>This entry includes Bet3 (also known as TRAPPC3) and Bet3-like (TRAPPC3L) proteins from eukaryotes. They seem to be involved in vesicle-mediated transport</p>. <p>Yeast Bet3 is a core component of transport protein particle (TRAPP) complexes I-III. The TRAPPI complex recognises the coat (COPII) on ER-derived vesicles, whereas the TRAPPII complex recognises the coat (COPI) on Golgi-derived vesicles [[cite:PUB00056043]]. TRAPPIII is responsible for vesicular transport from early endosomes to Golgi, facilitating Atg9 cycling in autophagy [[cite:PUB00075298]].</p> <p>Mammalian TRAPPs complexity is increased by the presence of multiple TRAPP homologues and novel subunits or binding proteins that are not part of the yeast TRAPP complexes [[cite:PUB00080272]]. Bet3 and its homologue Bet3-like are both components of the mammalian TRAPP complex [[cite:PUB00075414]].</p>
This description is obtained from EB-eye REST.
GO predictions are based solely on the InterPro-to-GO mappings published by EMBL-EBI, which are in turn based on the mapping of predicted domains to the InterPro dataset. The InterPro-to-GO mapping was last updated on , while the GO metadata was last updated on .
| GO term | Namespace | Name | Definition | Relationships |
|---|---|---|---|---|
| Cellular component | TRAPP complex | A large complex that acts as a tethering factor involved in transporting vesicles from the ER through the Golgi to the plasma membrane. A TRAPP (transport protein particle) complex has a core set of proteins which are joined by specific subunits depending on the cellular component where a given TRAPP complex is active. | ||
| Biological process | Golgi vesicle transport | The directed movement of substances into, out of or within the Golgi apparatus, mediated by vesicles. |
| Transcript | Name | Description | Predicted domains | Domain count |
|---|---|---|---|---|
| – | PREDICTED: trafficking protein particle complex subunit 3-like isoform X2 [Cicer arietinum] gi|502143721|ref|XP_004505441.1| | 10 | ||
| – | Trafficking protein particle complex subunit 3; TAIR: AT5G54750.1 Transport protein particle (TRAPP) component; Swiss-Prot: sp|Q5ZI57|TPPC3_CHICK Trafficking protein particle complex subunit 3; TrEMBL-Plants: tr|I3SMY8|I3SMY8_LOTJA Uncharacterized protein; Found in the gene: LotjaGi3g1v0149700 | 11 | ||
| – | Trafficking protein particle complex subunit 3; TAIR: AT5G54750.1 Transport protein particle (TRAPP) component; Swiss-Prot: sp|Q5ZI57|TPPC3_CHICK Trafficking protein particle complex subunit 3; TrEMBL-Plants: tr|I3SMY8|I3SMY8_LOTJA Uncharacterized protein; Found in the gene: LotjaGi3g1v0149700 | 11 |
A list of co-occurring predicted domains within the L. japonicus gene space:
| Predicted domain | Source | Observations | Saturation (%) |
|---|---|---|---|
| cd14942 | CDD | 1 | 33.33 |