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IPR017407

Source: InterPro

Description

IPR017407 is a Serine/threonine-protein kinase Rio1.

<p>This entry represents serine/threonine-protein kinases ([ec:2.7.11.1]) such as Rio1. RIO kinases are atypical members of the protein kinase family that are required for ribosome biogenesis and cell cycle progression [[cite:PUB00042768]]. Rio1 is present in all organisms from archaea to mammals, and was shown to be absolutely essential in Saccharomyces cerevisiae (Baker's yeast) for the processing of 18S ribosomal RNA, as well as for proper cell cycle progression and chromosome maintenance [[cite:PUB00020258]].</p>

This description is obtained from EB-eye REST.

Associated GO terms

GO predictions are based solely on the InterPro-to-GO mappings published by EMBL-EBI, which are in turn based on the mapping of predicted domains to the InterPro dataset. The InterPro-to-GO mapping was last updated on , while the GO metadata was last updated on .

GO term Namespace Name Definition Relationships
GO:0004674
Molecular function Protein serine/threonine kinase activity Catalysis of the reactions: ATP + protein serine = ADP + protein serine phosphate, and ATP + protein threonine = ADP + protein threonine phosphate.
Subterm of

Associated Lotus transcripts 2

Transcript Name Description Predicted domains Domain count
Lj1g3v2627670.1
– PREDICTED: serine/threonine-protein kinase RIO1-like [Glycine max] gi|356568362|ref|XP_003552380.1|
Domains
16
LotjaGi1g1v0472800.1
– Serine/threonine-protein kinase RIO1; TAIR: AT2G24990.1 Serine/threonine-protein kinase Rio1; Swiss-Prot: sp|Q9BRS2|RIOK1_HUMAN Serine/threonine-protein kinase RIO1; TrEMBL-Plants: tr|A0A151TBL1|A0A151TBL1_CAJCA Serine/threonine-protein kinase RIO1; Found in the gene: LotjaGi1g1v0472800
Domains
18

Co-occuring domains 1

A list of co-occurring predicted domains within the L. japonicus gene space:

Predicted domain Source Observations Saturation (%)
mobidb-lite MobiDBLite 1 50.00