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IPR017865 is a F-actin capping protein, alpha subunit, conserved site.
<p>The actin filament system, a prominent part of the cytoskeleton in eukaryotic cells, is both a static structure and a dynamic network that can undergo rearrangements: it is thought to be involved in processes such as cell movement and phagocytosis [[cite:PUB00002626]], as well as muscle contraction.</p> <p>The F-actin capping protein binds in a calcium-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike gelsolin and severin this protein does not sever actin filaments. The F-actin capping protein is a heterodimer composed of two unrelated subunits: alpha and beta (see [interpro:IPR001698]). Neither of the subunits shows sequence similarity to other filament-capping proteins [[cite:PUB00002626]].</p> <p>The alpha subunit is a protein of about 268 to 286 amino acid residues whose sequence is well conserved in eukaryotic species [[cite:PUB00000981]].</p>
This description is obtained from EB-eye REST.
| Transcript | Name | Description | Predicted domains | Domain count |
|---|---|---|---|---|
| – | F-actin-capping protein subunit alpha; TAIR: AT3G05520.2 Subunits of heterodimeric actin filament capping protein Capz superfamily; Swiss-Prot: sp|O82631|CAPZA_ARATH F-actin-capping protein subunit alpha; TrEMBL-Plants: tr|I3SNV9|I3SNV9_LOTJA Uncharacterized protein; Found in the gene: LotjaGi1g1v0770500 | 14 |
A list of co-occurring predicted domains within the L. japonicus gene space:
| Predicted domain | Source | Observations | Saturation (%) |
|---|---|---|---|
| SSF90096 | SUPERFAMILY | 1 | 100.00 |