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IPR018232

Description

IPR018232 is a Glycoside hydrolase, family 37, conserved site.

<p>O-Glycosyl hydrolases ([ec:3.2.1.]) are a widespread group of enzymes that hydrolyse the glycosidic bond between two or more carbohydrates, or between a carbohydrate and a non-carbohydrate moiety. A classification system for glycosyl hydrolases, based on sequence similarity, has led to the definition of 85 different families [[cite:PUB00004870], [cite:PUB00005266]]. This classification is available on the CAZy (CArbohydrate-Active EnZymes) website.</p> <p>Glycoside hydrolase family 37 [cazy:GH37] comprises enzymes with only one known activity; trehalase ([ec:3.2.1.28]).</p> <p>Trehalase is the enzyme responsible for the degradation of the disaccharide alpha,alpha-trehalose yielding two glucose subunits [[cite:PUB00002824]]. It is an enzyme found in a wide variety of organisms and whose sequence has been highly conserved throughout evolution.</p>

This description is obtained from EB-eye REST.

Associated GO terms

GO predictions are based solely on the InterPro-to-GO mappings published by EMBL-EBI, which are in turn based on the mapping of predicted domains to the InterPro dataset. The InterPro-to-GO mapping was last updated on , while the GO metadata was last updated on .

GO term Namespace Name Definition Relationships
Molecular function Alpha,alpha-trehalase activity Catalysis of the reaction: alpha,alpha-trehalose + H2O = 2 D-glucose.
Biological process Trehalose metabolic process The chemical reactions and pathways involving trehalose, a disaccharide isomeric with sucrose and obtained from certain lichens and fungi.

Associated Lotus transcripts 4

Transcript Name Description Predicted domains Domain count
PREDICTED: trehalase-like isoform X1 [Cicer arietinum] gi|502138911|ref|XP_004503574.1| 9
PREDICTED: trehalase-like isoform X1 [Cicer arietinum] gi|502138911|ref|XP_004503574.1| 18
Trehalase; TAIR: AT4G24040.1 trehalase 1; Swiss-Prot: sp|Q9FWC1|TRE_ORYSJ Probable trehalase; TrEMBL-Plants: tr|I1K665|I1K665_SOYBN Trehalase; Found in the gene: LotjaGi4g1v0438200 11
Trehalase; TAIR: AT4G24040.1 trehalase 1; Swiss-Prot: sp|Q9FWC1|TRE_ORYSJ Probable trehalase; TrEMBL-Plants: tr|I1K665|I1K665_SOYBN Trehalase; Found in the gene: LotjaGi4g1v0438200 19

Co-occuring domains 1

A list of co-occurring predicted domains within the L. japonicus gene space:

Predicted domain Source Observations Saturation (%)
TMhelix TMHMM 1 25.00