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IPR018864

Source: InterPro

Description

IPR018864 is a Nucleoporin Nup188, N-terminal.

<p>This protein folds into an extended stack of helices where the N-terminal forms a closed ring (subdivided into subdomains I-III in [[cite:PUB00091656]]) and the C-terminal forms a more regular, superhelical structure [[cite:PUB00091656]]. This entry represents the N-terminal helical repeats from Nup188.</p> <p>Nup188 is one of the many peptides that make up the nucleoporin complex (NPC), and is found across eukaryotes [[cite:PUB00044405]]. The Nup188 subcomplex (Nic96p-Nup188p-Nup192p-Pom152p) is one of at least six that make up the NPC, and as such is symmetrically localised on both faces of the NPC at the nuclear end, being integrally bound to the C terminus of Pom34p [[cite:PUB00044406]].</p>

This description is obtained from EB-eye REST.

Associated GO terms

GO predictions are based solely on the InterPro-to-GO mappings published by EMBL-EBI, which are in turn based on the mapping of predicted domains to the InterPro dataset. The InterPro-to-GO mapping was last updated on , while the GO metadata was last updated on .

GO term Namespace Name Definition Relationships
GO:0017056
Molecular function Structural constituent of nuclear pore The action of a molecule that contributes to the structural integrity of the nuclear pore complex, a protein-lined channel in the nuclear envelope that allows the transfer of macromolecules.
Subterm of

Associated Lotus transcripts 1

Transcript Name Description Predicted domains Domain count
Lj0g3v0129799.1
– Nucleoporin NUP188-like protein [Medicago truncatula] gi|357473981|ref|XP_003607275.1|
Domains
7

Co-occuring domains 1

A list of co-occurring predicted domains within the L. japonicus gene space:

Predicted domain Source Observations Saturation (%)
TRANSMEMBRANE Phobius 1 100.00