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IPR021843 is a Proteasome activator complex subunit 4 C-terminal domain.
<p>This domain is typically between 142 to 163 amino acids in length is found at the C terminus of activator complex subunit 4 (gene name PSME4, PA2000 or BLM10), a component of the 19S cap complex of the eukaryotic 26S proteasome. The tertiary structure of BLM10 from<i>Saccharomyces cerevisiae</i>has been solved, showing that the C terminus is important for helping to form the BLM10 cap that covers the entry pore of the proteasome, restricting access for potential substrates. The C-terminal residues bind in the pocket between proteasome subunits alpha5 and alpha6, in a similar site to where the C-termini of the ATPases of the 19S proteasomal cap also bind [[cite:PUB00076285]].</p>
This description is obtained from EB-eye REST.
| Transcript | Name | Description | Predicted domains | Domain count |
|---|---|---|---|---|
| – | PREDICTED: proteasome activator complex subunit 4-like isoform 1 [Glycine max] gi|356527200|ref|XP_003532200.1| | 15 | ||
| – | Proteasome activator subunit 4; TAIR: AT3G13330.1 proteasome activating protein 200; Swiss-Prot: sp|F4JC97|PSME4_ARATH Proteasome activator subunit 4; TrEMBL-Plants: tr|I1N058|I1N058_SOYBN Uncharacterized protein; Found in the gene: LotjaGi6g1v0136800 | 11 |
A list of co-occurring predicted domains within the L. japonicus gene space:
| Predicted domain | Source | Observations | Saturation (%) |
|---|---|---|---|
| SSF48371 | SUPERFAMILY | 1 | 50.00 |