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IPR022412

Source: InterPro

Description

IPR022412 is a Quinolinate phosphoribosyl transferase, N-terminal.

<p>Quinolinate phosphoribosyl transferase (QPRTase) or nicotinate-nucleotide pyrophosphorylase [ec:2.4.2.19] is involved in the<i>de novo</i>synthesis of NAD in both prokaryotes and eukaryotes. It catalyses the reaction of quinolinic acid with 5-phosphoribosyl-1-pyrophosphate (PRPP) in the presence of Mg<sup>2+</sup>to give rise to nicotinic acid mononucleotide (NaMN), pyrophosphate and carbon dioxide [[cite:PUB00005289], [cite:PUB00000163]]. Unlike [interpro:IPR004393], this domain also includes the molybdenum transport system protein ModD.</p>

This description is obtained from EB-eye REST.

Associated GO terms

GO predictions are based solely on the InterPro-to-GO mappings published by EMBL-EBI, which are in turn based on the mapping of predicted domains to the InterPro dataset. The InterPro-to-GO mapping was last updated on , while the GO metadata was last updated on .

GO term Namespace Name Definition Relationships
GO:0016763
Molecular function Transferase activity, transferring pentosyl groups Catalysis of the transfer of a pentosyl group from one compound (donor) to another (acceptor).
Subterm of

Associated Lotus transcripts 6

Transcript Name Description Predicted domains Domain count
LotjaGi2g1v0061600.1
– Nicotinate-nucleotide pyrophosphorylase [carboxylating]; TAIR: AT2G01350.1 quinolinate phoshoribosyltransferase; Swiss-Prot: sp|Q9ZU32|NADC_ARATH Nicotinate-nucleotide pyrophosphorylase [carboxylating], chloroplastic; TrEMBL-Plants: tr|A0A072VQY4|A0A072VQY4_MEDTR Quinolinate phosphoribosyltransferase, putative; Found in the gene: LotjaGi2g1v0061600
Domains
18
LotjaGi2g1v0061600.2
– Nicotinate-nucleotide pyrophosphorylase [carboxylating]; TAIR: AT2G01350.1 quinolinate phoshoribosyltransferase; Swiss-Prot: sp|Q9ZU32|NADC_ARATH Nicotinate-nucleotide pyrophosphorylase [carboxylating], chloroplastic; TrEMBL-Plants: tr|A0A0B2RX79|A0A0B2RX79_GLYSO Putative nicotinate-nucleotide pyrophosphorylase [carboxylating]; Found in the gene: LotjaGi2g1v0061600
Domains
19
LotjaGi2g1v0061600.3
– Nicotinate-nucleotide pyrophosphorylase [carboxylating]; TAIR: AT2G01350.1 quinolinate phoshoribosyltransferase; Swiss-Prot: sp|Q9ZU32|NADC_ARATH Nicotinate-nucleotide pyrophosphorylase [carboxylating], chloroplastic; TrEMBL-Plants: tr|A0A0B2S2R6|A0A0B2S2R6_GLYSO Putative nicotinate-nucleotide pyrophosphorylase [carboxylating]; Found in the gene: LotjaGi2g1v0061600
Domains
18
LotjaGi2g1v0061600.4
– Nicotinate-nucleotide pyrophosphorylase [carboxylating]; TAIR: AT2G01350.1 quinolinate phoshoribosyltransferase; Swiss-Prot: sp|Q9ZU32|NADC_ARATH Nicotinate-nucleotide pyrophosphorylase [carboxylating], chloroplastic; TrEMBL-Plants: tr|A0A0B2RX79|A0A0B2RX79_GLYSO Putative nicotinate-nucleotide pyrophosphorylase [carboxylating]; Found in the gene: LotjaGi2g1v0061600
Domains
18
LotjaGi2g1v0061600.5
– Nicotinate-nucleotide pyrophosphorylase [carboxylating]; TAIR: AT2G01350.1 quinolinate phoshoribosyltransferase; Swiss-Prot: sp|Q9ZU32|NADC_ARATH Nicotinate-nucleotide pyrophosphorylase [carboxylating], chloroplastic; TrEMBL-Plants: tr|A0A0B2S2R6|A0A0B2S2R6_GLYSO Putative nicotinate-nucleotide pyrophosphorylase [carboxylating]; Found in the gene: LotjaGi2g1v0061600
Domains
17
LotjaGi2g1v0061600.6
– Nicotinate-nucleotide pyrophosphorylase [carboxylating]; TAIR: AT2G01350.1 quinolinate phoshoribosyltransferase; Swiss-Prot: sp|Q9ZU32|NADC_ARATH Nicotinate-nucleotide pyrophosphorylase [carboxylating], chloroplastic; TrEMBL-Plants: tr|A0A0B2S2R6|A0A0B2S2R6_GLYSO Putative nicotinate-nucleotide pyrophosphorylase [carboxylating]; Found in the gene: LotjaGi2g1v0061600
Domains
16

Co-occuring domains 1

A list of co-occurring predicted domains within the L. japonicus gene space:

Predicted domain Source Observations Saturation (%)
cd01572 CDD 1 16.67