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IPR022677 is a Glycylpeptide N-tetradecanoyltransferase, C-terminal.
<p>Glycylpeptide N-tetradecanoyltransferase, also known as Myristoyl-CoA:protein N-myristoyltransferase ([ec:2.3.1.97]) (Nmt), is the enzyme responsible for transferring a myristate group on the N-terminal glycine of a number of cellular eukaryotics and viral proteins [[cite:PUB00000005]]. Nmt is a monomeric protein of about 50 to 60kDa whose sequence appears to be well conserved. In Drosophila, this protein is critical for the developmental processes that involve cell shape changes and movement [[cite:PUB00100072]].</p> <p>The N and C-terminal domains of NMT are structurally similar, each adopting an acyl-CoA N-acyltransferase-like fold. This entry represents the C-terminal region [[cite:PUB00019930]].</p>
This description is obtained from EB-eye REST.
GO predictions are based solely on the InterPro-to-GO mappings published by EMBL-EBI, which are in turn based on the mapping of predicted domains to the InterPro dataset. The InterPro-to-GO mapping was last updated on , while the GO metadata was last updated on .
| GO term | Namespace | Name | Definition | Relationships |
|---|---|---|---|---|
| Molecular function | Glycylpeptide N-tetradecanoyltransferase activity | Catalysis of the reaction: tetradecanoyl-CoA + glycyl-peptide = CoA + N-tetradecanoylglycyl-peptide. |
| Transcript | Name | Description | Predicted domains | Domain count |
|---|---|---|---|---|
| – | Glycylpeptide N-tetradecanoyltransferase; TAIR: AT5G57020.1 myristoyl-CoA:protein N-myristoyltransferase; Swiss-Prot: sp|Q9LTR9|NMT1_ARATH Glycylpeptide N-tetradecanoyltransferase 1; TrEMBL-Plants: tr|A0A072UXN8|A0A072UXN8_MEDTR Glycylpeptide N-tetradecanoyltransferase; Found in the gene: LotjaGi3g1v0420700 | 15 | ||
| – | Glycylpeptide N-tetradecanoyltransferase; TAIR: AT5G57020.1 myristoyl-CoA:protein N-myristoyltransferase; Swiss-Prot: sp|Q9LTR9|NMT1_ARATH Glycylpeptide N-tetradecanoyltransferase 1; TrEMBL-Plants: tr|A0A072UXN8|A0A072UXN8_MEDTR Glycylpeptide N-tetradecanoyltransferase; Found in the gene: LotjaGi3g1v0420700 | 15 | ||
| – | Glycylpeptide N-tetradecanoyltransferase; TAIR: AT5G57020.1 myristoyl-CoA:protein N-myristoyltransferase; Swiss-Prot: sp|Q9LTR9|NMT1_ARATH Glycylpeptide N-tetradecanoyltransferase 1; TrEMBL-Plants: tr|A0A072UXN8|A0A072UXN8_MEDTR Glycylpeptide N-tetradecanoyltransferase; Found in the gene: LotjaGi3g1v0420700 | 15 | ||
| – | Glycylpeptide N-tetradecanoyltransferase; TAIR: AT5G57020.1 myristoyl-CoA:protein N-myristoyltransferase; Swiss-Prot: sp|Q9LTR9|NMT1_ARATH Glycylpeptide N-tetradecanoyltransferase 1; TrEMBL-Plants: tr|I3SJW0|I3SJW0_LOTJA Glycylpeptide N-tetradecanoyltransferase; Found in the gene: LotjaGi6g1v0229700 | 15 | ||
| – | Glycylpeptide N-tetradecanoyltransferase; TAIR: AT5G57020.1 myristoyl-CoA:protein N-myristoyltransferase; Swiss-Prot: sp|Q9LTR9|NMT1_ARATH Glycylpeptide N-tetradecanoyltransferase 1; TrEMBL-Plants: tr|I3SJW0|I3SJW0_LOTJA Glycylpeptide N-tetradecanoyltransferase; Found in the gene: LotjaGi6g1v0229700 | 15 | ||
| – | Glycylpeptide N-tetradecanoyltransferase; TAIR: AT5G57020.1 myristoyl-CoA:protein N-myristoyltransferase; Swiss-Prot: sp|Q9LTR9|NMT1_ARATH Glycylpeptide N-tetradecanoyltransferase 1; TrEMBL-Plants: tr|I3SJW0|I3SJW0_LOTJA Glycylpeptide N-tetradecanoyltransferase; Found in the gene: LotjaGi6g1v0229700 | 15 |
A list of co-occurring predicted domains within the L. japonicus gene space:
| Predicted domain | Source | Observations | Saturation (%) |
|---|---|---|---|
| mobidb-lite | MobiDBLite | 1 | 16.67 |