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IPR022771

Source: InterPro

Description

IPR022771 is a Wings apart-like protein, C-terminal.

<p>This entry represents the conserved region of D. melanogaster wings apart-like protein, WAPL. It is involved in the regulation of heterochromatin structure [[cite:PUB00016495]]. hWAPL ([swissprot:Q7Z5K2]), the human homologue, is found to play a role in the development of cervical carcinogenesis, and is thought to have similar functions to Drosophila wapl protein [[cite:PUB00016544]]. Malfunction of the hWAPL pathway is thought to activate an apoptotic pathway that consequently leads to cell death [[cite:PUB00016544]].</p> <p>The WAPL-like proteins can be found in metazoa, fungi and plants.</p>

This description is obtained from EB-eye REST.

Associated GO terms

Unable to find any GO terms for the transcript with the identifier.

Associated Lotus transcripts 6

Transcript Name Description Predicted domains Domain count
Lj0g3v0282079.1
– WAPL (Wings apart-like protein regulation of heterochromatin) protein [Arabidopsis thaliana] gi|30682037|ref|NP_172573.2|
Domains
4
Lj4g3v0450800.1
– WAPL (Wings apart-like protein regulation of heterochromatin) protein [Arabidopsis thaliana] gi|30682037|ref|NP_172573.2|
Domains
9
Lj6g3v2044470.2
– WAPL (Wings apart-like protein regulation of heterochromatin) protein [Arabidopsis thaliana] gi|15219850|ref|NP_176298.1|
Domains
4
LotjaGi4g1v0054000.1
– Wings apart-like protein like; TAIR: AT1G11060.1 WAPL (Wings apart-like protein regulation of heterochromatin) protein; Swiss-Prot: sp|Q7Z5K2|WAPL_HUMAN Wings apart-like protein homolog; TrEMBL-Plants: tr|A0A072UNY9|A0A072UNY9_MEDTR WAPL (Wings apart-like protein regulation of heterochromatin) protein, putative; Found in the gene: LotjaGi4g1v0054000
Domains
11
LotjaGi6g1v0334600_LC.1
– Wings apart-like protein like; TAIR: AT1G61030.1 WAPL (Wings apart-like protein regulation of heterochromatin) protein; Swiss-Prot: sp|A9KNK6|PNP_CLOPH Polyribonucleotide nucleotidyltransferase; TrEMBL-Plants: tr|V7CPL5|V7CPL5_PHAVU Uncharacterized protein; Found in the gene: LotjaGi6g1v0334600_LC
Domains
6
LotjaGi6g1v0334700.1
– Wings apart-like protein like; TAIR: AT1G61030.1 WAPL (Wings apart-like protein regulation of heterochromatin) protein; Swiss-Prot: sp|Q65Z40|WAPL_MOUSE Wings apart-like protein homolog; TrEMBL-Plants: tr|V7CPL5|V7CPL5_PHAVU Uncharacterized protein; Found in the gene: LotjaGi6g1v0334700
Domains
7

Co-occuring domains 1

A list of co-occurring predicted domains within the L. japonicus gene space:

Predicted domain Source Observations Saturation (%)
PTHR22100 PANTHER 1 16.67