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IPR024185 is a 5-formyltetrahydrofolate cyclo-ligase-like domain superfamily.
<p>This superfamily represents a domain found in 5-formyltetrahydrofolate cyclo-ligase, also known as 5,10-methenyltetrahydrofolate synthetase. This enzyme is involved in folate metabolism. It is a single-domain alpha/beta protein. The central core of the protein is a four-stranded parallel β-strand flanked by three helices on one side and a single helix on the other side [[cite:PUB00030982]]. This domain is also found in LutC/YkgG. The Escherichia coli ykgEFG operon is a clear homologue of the Bacillus subtilis lutABC operon. This operon is involved in lactate catabolism in B. subtilis, though its role in E. coli is not clear. LutB and LutC probably act as electron transporters during oxidation of L-lactate [[cite:PUB00053899]].</p>
This description is obtained from EB-eye REST.
| Transcript | Name | Description | Predicted domains | Domain count |
|---|---|---|---|---|
| – | PREDICTED: methenyltetrahydrofolate synthase domain-containing protein-like [Cicer arietinum] gi|502164511|ref|XP_004513147.1| | 8 | ||
| – | PREDICTED: 5-formyltetrahydrofolate cyclo-ligase-like isoform X1 [Cicer arietinum] gi|502093532|ref|XP_004489971.1| | 8 | ||
| – | 5-formyltetrahydrofolate cyclo-ligase; TAIR: AT5G13050.1 5-formyltetrahydrofolate cycloligase; Swiss-Prot: sp|Q8L539|5FCL_ARATH 5-formyltetrahydrofolate cyclo-ligase, mitochondrial; TrEMBL-Plants: tr|A0A0B2QHY4|A0A0B2QHY4_GLYSO 5-formyltetrahydrofolate cyclo-ligase; Found in the gene: LotjaGi1g1v0186100 | 9 | ||
| – | 5-formyltetrahydrofolate cyclo-ligase; TAIR: AT1G76730.1 NagB/RpiA/CoA transferase-like superfamily protein; Swiss-Prot: sp|Q9SRE0|5FCLL_ARATH 5-formyltetrahydrofolate cyclo-ligase-like protein COG0212; TrEMBL-Plants: tr|A0A0L9VLB2|A0A0L9VLB2_PHAAN Uncharacterized protein; Found in the gene: LotjaGi2g1v0128300 | 8 |
A list of co-occurring predicted domains within the L. japonicus gene space:
| Predicted domain | Source | Observations | Saturation (%) |
|---|---|---|---|
| mobidb-lite | MobiDBLite | 1 | 25.00 |