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IPR025160 is a AATF leucine zipper-containing domain.
<p>This leucine zipper-containing domain is found in apoptosis antagonizing transcription factor (AATF, also known as Che-1) and related proteins. AATF may function as a general inhibitor of the histone deacetylase HDAC1 [[cite:PUB00057306]]. AATF has been shown to inhibit the abberant production of the amyloid beta peptide 1-42 by direct interaction with Par4 [[cite:PUB00057401]]. This interaction occurs via the leucine zipper.</p>
This description is obtained from EB-eye REST.
Transcript | Name | Description | Predicted domains | Domain count |
---|---|---|---|---|
– | PREDICTED: protein AATF-like [Glycine max] gi|356568608|ref|XP_003552502.1| | 8 | ||
– | Protein AATF; TAIR: AT5G61330.1 rRNA processing protein-like protein; Swiss-Prot: sp|Q5ZIM6|AATF_CHICK Protein AATF; TrEMBL-Plants: tr|I1N489|I1N489_SOYBN Uncharacterized protein; Found in the gene: LotjaGi1g1v0051900 | 8 |
A list of co-occurring predicted domains within the L. japonicus gene space:
Predicted domain | Source | Observations | Saturation (%) |
---|---|---|---|
mobidb-lite | MobiDBLite | 1 | 50.00 |