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IPR039223 is a Protein AATF/Bfr2.
<p>Apoptosis antagonizing transcription factor (AATF, also known as Che-1) is a adaptor that connects transcriptional regulation, cell-cycle progression, checkpoint control, and apoptosis [[cite:PUB00089516]]. It contains a leucine zipper-containing domain [[cite:PUB00057306]]. AATF has been shown to inhibit the aberrant production of the amyloid beta peptide 1-42 by direct interaction with Par4; this interaction occurs via the leucine zipper. [[cite:PUB00057401]]. AATF has also been shown to form a nucleolar protein complex with NGDN and NOL10 required for 40S ribosomal subunit synthesis [[cite:PUB00089515]].</p> <p>This entry also includes the yeast protein Bfr2, which is a component of the SSU processome and 90S preribosomes [[cite:PUB00089514]].</p>
This description is obtained from EB-eye REST.
| Transcript | Name | Description | Predicted domains | Domain count |
|---|---|---|---|---|
| – | Protein AATF; TAIR: AT5G61330.1 rRNA processing protein-like protein; Swiss-Prot: sp|Q5ZIM6|AATF_CHICK Protein AATF; TrEMBL-Plants: tr|I1N489|I1N489_SOYBN Uncharacterized protein; Found in the gene: LotjaGi1g1v0051900 | 8 |
A list of co-occurring predicted domains within the L. japonicus gene space:
| Predicted domain | Source | Observations | Saturation (%) |
|---|---|---|---|
| mobidb-lite | MobiDBLite | 1 | 100.00 |