Your browser is unable to support new features implemented in HTML5 and CSS3 to render this site as intended. Your experience may suffer from functionality degradation but the site should remain usable. We strongly recommend the latest version of Google Chrome, OS X Safari or Mozilla Firefox. As Safari is bundled with OS X, if you are unable to upgrade to a newer version of OS X, we recommend using an open source browser. Dismiss message
IPR025662 is a Sigma-54 interaction domain, ATP-binding site 1.
<p>Some bacterial regulatory proteins activate the expression of genes from promoters recognised by core RNA polymerase associated with the alternative sigma-54 factor. These have a conserved domain of about 230 residues involved in the ATP-dependent [[cite:PUB00002228], [cite:PUB00004389]] interaction with sigma-54. About half of the proteins in which this domain is found (algB, dcdT, flbD, hoxA, hupR1, hydG, ntrC, pgtA and pilR) belong to signal transduction two-component systems [[cite:PUB00000103]] and possess a domain that can be phosphorylated by a sensor-kinase protein in their N-terminal section. Almost all of these proteins possess a helix-turn-helix DNA-binding domain in their C-terminal section.</p> <p>The domain involved in interaction with the sigma-54 factor has an ATPase activity. This may be required to promote a conformational change necessary for the interaction [[cite:PUB00001221]]. The domain contains an atypical ATP-binding motif A (P-loop) as well as a form of motif B.</p> <p>This entry represents a conserved site corresponding to the first ATP-binding motif located in the N-terminal section of the sigma-54 interaction domain.</p>
This description is obtained from EB-eye REST.
| Transcript | Name | Description | Predicted domains | Domain count |
|---|---|---|---|---|
| – | PREDICTED: LOW QUALITY PROTEIN: midasin-like [Cicer arietinum] gi|502156332|ref|XP_004510421.1| | 14 | ||
| – | Ras-related small GTP-binding family protein [Theobroma cacao] gi|508700403|gb|EOX92299.1| | 13 | ||
| – | Midasin; TAIR: AT1G67120.1 midasin-like protein; Swiss-Prot: sp|Q869L3|MDN1_DICDI Midasin; TrEMBL-Plants: tr|K7MEE0|K7MEE0_SOYBN Midasin; Found in the gene: LotjaGi3g1v0418800 | 23 | ||
| – | Ras-related protein Rab-3; TAIR: AT5G64813.1 Ras-related small GTP-binding family protein; Swiss-Prot: sp|Q9C5J9|LIIP1_ARATH Small GTPase LIP1; TrEMBL-Plants: tr|V7CQY4|V7CQY4_PHAVU Uncharacterized protein; Found in the gene: LotjaGi4g1v0403900 | 13 |
A list of co-occurring predicted domains within the L. japonicus gene space:
| Predicted domain | Source | Observations | Saturation (%) |
|---|---|---|---|
| mobidb-lite | MobiDBLite | 1 | 25.00 |