Your browser is unable to support new features implemented in HTML5 and CSS3 to render this site as intended. Your experience may suffer from functionality degradation but the site should remain usable. We strongly recommend the latest version of Google Chrome, OS X Safari or Mozilla Firefox. As Safari is bundled with OS X, if you are unable to upgrade to a newer version of OS X, we recommend using an open source browser. Dismiss message
IPR025787 is a Histone-lysine N-methyltransferase, SET2, plant.
<p>ASHR3 protein, a member of this family, interacts with the putative basic helix-loop-helix transcription factor ABORTED MICROSPORES (AMS), which is involved in anther and stamen development in Arabidopsis. This interaction is mediated by the PHD finger and the SET domain of ASHR3 [[cite:PUB00058020]].</p> <p>Methyltransferases (EC [ec:2.1.1.-]) constitute an important class of enzymes present in every life form. They transfer a methyl group most frequently from S-adenosyl L-methionine (SAM or AdoMet) to a nucleophilic acceptor such as oxygen leading to S-adenosyl-L-homocysteine (AdoHcy) and a methylated molecule [[cite:PUB00057957], [cite:PUB00057958], [cite:PUB00054125]]. All these enzymes have in common a conserved region of about 130 amino acid residues that allow them to bind SAM [[cite:PUB00006319]]. The substrates that are methylated by these enzymes cover virtually every kind of biomolecules ranging from small molecules, to lipids, proteins and nucleic acids [[cite:PUB00057957], [cite:PUB00057958], [cite:PUB00006319]]. Methyltransferase are therefore involved in many essential cellular processes including biosynthesis, signal transduction, protein repair, chromatin regulation and gene silencing [[cite:PUB00057957], [cite:PUB00057958], [cite:PUB00054125]]. More than 230 families of methyltransferases have been described so far, of which more than 220 use SAM as the methyl donor.</p>
This description is obtained from EB-eye REST.
| Transcript | Name | Description | Predicted domains | Domain count |
|---|---|---|---|---|
| – | PREDICTED: histone-lysine N-methyltransferase ASHH3-like [Glycine max] gi|356530969|ref|XP_003534051.1| | 17 | ||
| – | PREDICTED: histone-lysine N-methyltransferase ASHR3-like [Glycine max] gi|356514491|ref|XP_003525939.1| | 17 | ||
| – | PREDICTED: histone-lysine N-methyltransferase ASHR3-like, partial [Cucumis sativus] gi|449530608|ref|XP_004172286.1| | 15 | ||
| – | Histone-lysine N-methyltransferase; TAIR: AT2G44150.1 histone-lysine N-methyltransferase ASHH3; Swiss-Prot: sp|Q945S8|ASHH3_ARATH Histone-lysine N-methyltransferase ASHH3; TrEMBL-Plants: tr|A0A0B2NX70|A0A0B2NX70_GLYSO Histone-lysine N-methyltransferase ASHH3; Found in the gene: LotjaGi2g1v0165900 | 17 | ||
| – | Histone-lysine N-methyltransferase; TAIR: AT2G44150.1 histone-lysine N-methyltransferase ASHH3; Swiss-Prot: sp|Q945S8|ASHH3_ARATH Histone-lysine N-methyltransferase ASHH3; TrEMBL-Plants: tr|A0A0B2NX70|A0A0B2NX70_GLYSO Histone-lysine N-methyltransferase ASHH3; Found in the gene: LotjaGi2g1v0165900 | 17 | ||
| – | Histone-lysine N-methyltransferase; TAIR: AT4G30860.1 SET domain group 4; Swiss-Prot: sp|Q949T8|ASHR3_ARATH Histone-lysine N-methyltransferase ASHR3; TrEMBL-Plants: tr|A0A0L9UBQ6|A0A0L9UBQ6_PHAAN Uncharacterized protein; Found in the gene: LotjaGi6g1v0199300 | 21 |
A list of co-occurring predicted domains within the L. japonicus gene space:
| Predicted domain | Source | Observations | Saturation (%) |
|---|---|---|---|
| mobidb-lite | MobiDBLite | 1 | 16.67 |