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IPR028211 is a Pre-mRNA-splicing factor Ntr2.
<p>This entry represents the pre-mRNA-splicing factor Ntr2.</p> <p>In Saccharomyces cerevisiae, Ntr1 and Ntr2 (nineTeen complex-Related proteins) formed a stable complex with DExD/H-box RNA helicase Prp43, which is involved in disassembly of the spliceosome and release of the excised intron in its branched, lariat form [[cite:PUB00067694]]. Ntr1 is required for the association of Prp43 with the excised intron complex prior to its release and recycling of the splicing factors [[cite:PUB00054039]]. Ntr2 can associate with late splicing complexes independently of Ntr1 but is not by itself sufficient to activate the intron release function of Prp43 [[cite:PUB00067694]].</p>
This description is obtained from EB-eye REST.
GO predictions are based solely on the InterPro-to-GO mappings published by EMBL-EBI, which are in turn based on the mapping of predicted domains to the InterPro dataset. The InterPro-to-GO mapping was last updated on , while the GO metadata was last updated on .
| GO term | Namespace | Name | Definition | Relationships |
|---|---|---|---|---|
| Biological process | Spliceosomal complex disassembly | Disassembly of a spliceosomal complex with the ATP-dependent release of the product RNAs, one of which is composed of the joined exons. In cis splicing, the other product is the excised sequence, often a single intron, in a lariat structure. | ||
| Cellular component | U2-type post-mRNA release spliceosomal complex | A spliceosomal complex that is formed following the release of the spliced product from the post-spliceosomal complex and contains the excised intron and the U2, U5 and U6 snRNPs. |
| Transcript | Name | Description | Predicted domains | Domain count |
|---|---|---|---|---|
| – | PREDICTED: GC-rich sequence DNA-binding factor 1-like [Glycine max] gi|356577171|ref|XP_003556701.1| | 9 |
A list of co-occurring predicted domains within the L. japonicus gene space:
| Predicted domain | Source | Observations | Saturation (%) |
|---|---|---|---|
| mobidb-lite | MobiDBLite | 1 | 100.00 |