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IPR028357

Source: InterPro

Description

IPR028357 is a UDP-glucose 6-dehydrogenase, bacterial type.

<p>UDP-glucose 6-dehydrogenase is involved in the biosynthesis of UDP-glucuronic acid (UDP-GlcA), a critical precursor for glycan synthesis. This process is required for capsule synthesis in some bacteria [[cite:PUB00068163], [cite:PUB00068161], [cite:PUB00068162]]. This entry represents bacterial type of the UDP-glucose 6-dehydrogenases. However, some non-bacterial proteins can also be found in this entry. This entry does not contain human UDP-glucose 6-dehydrogenase, which can be found in the eukaryotic type of the UDP-glucose 6-dehydrogenase ([interpro:IPR028356]).</p>

This description is obtained from EB-eye REST.

Associated GO terms

GO predictions are based solely on the InterPro-to-GO mappings published by EMBL-EBI, which are in turn based on the mapping of predicted domains to the InterPro dataset. The InterPro-to-GO mapping was last updated on , while the GO metadata was last updated on .

GO term Namespace Name Definition Relationships
GO:0000271
Biological process Polysaccharide biosynthetic process The chemical reactions and pathways resulting in the formation of a polysaccharide, a polymer of many (typically more than 10) monosaccharide residues linked glycosidically.
Subterm of
GO:0003979
Molecular function UDP-glucose 6-dehydrogenase activity Catalysis of the reaction: H(2)O + 2 NAD(+) + UDP-alpha-D-glucose = 3 H(+) + 2 NADH + UDP-alpha-D-glucuronate.
Subterm of

Associated Lotus transcripts 1

Transcript Name Description Predicted domains Domain count
Lj2g3v1254010.1
–
Domains
21

Co-occuring domains 1

A list of co-occurring predicted domains within the L. japonicus gene space:

Predicted domain Source Observations Saturation (%)
SSF52413 SUPERFAMILY 1 100.00