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IPR028592

Description

IPR028592 is a Queuine tRNA-ribosyltransferase accessory subunit QTRTD1.

<p>Queuine tRNA-ribosyltransferase accessory subunit 2 (Qtrt2 or QTRTD1) interacts with QTRT1 to form an active queuine tRNA-ribosyltransferase. It exchanges queuine for the guanine at the wobble position of tRNAs with GUN anticodons (tRNA-Asp, -Asn, -His and -Tyr), thereby forming the hypermodified nucleoside queuosine (Q) (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) [[cite:PUB00068811]].</p>

This description is obtained from EB-eye REST.

Associated GO terms

GO predictions are based solely on the InterPro-to-GO mappings published by EMBL-EBI, which are in turn based on the mapping of predicted domains to the InterPro dataset. The InterPro-to-GO mapping was last updated on , while the GO metadata was last updated on .

GO term Namespace Name Definition Relationships
Biological process TRNA modification The covalent alteration of one or more nucleotides within a tRNA molecule to produce a tRNA molecule with a sequence that differs from that coded genetically.
Molecular function Queuine tRNA-ribosyltransferase activity Catalysis of the reaction: tRNA guanine + queuine = tRNA queuine + guanine.

Associated Lotus transcripts 2

Transcript Name Description Predicted domains Domain count
Queuine tRNA-ribosyltransferase; TAIR: AT3G54050.1 high cyclic electron flow 1; Swiss-Prot: sp|Q28DX0|QTRT2_XENTR Queuine tRNA-ribosyltransferase accessory subunit 2; TrEMBL-Plants: tr|C6T7F2|C6T7F2_SOYBN Putative uncharacterized protein; Found in the gene: LotjaGi1g1v0510800 9
Queuine tRNA-ribosyltransferase; TAIR: AT3G54050.1 high cyclic electron flow 1; Swiss-Prot: sp|Q9H974|QTRT2_HUMAN Queuine tRNA-ribosyltransferase accessory subunit 2; TrEMBL-Plants: tr|C6T7F2|C6T7F2_SOYBN Putative uncharacterized protein; Found in the gene: LotjaGi1g1v0510800 9

Co-occuring domains 1

A list of co-occurring predicted domains within the L. japonicus gene space:

Predicted domain Source Observations Saturation (%)
TIGR00449 TIGRFAM 1 50.00