Your browser is unable to support new features implemented in HTML5 and CSS3 to render this site as intended. Your experience may suffer from functionality degradation but the site should remain usable. We strongly recommend the latest version of Google Chrome, OS X Safari or Mozilla Firefox. As Safari is bundled with OS X, if you are unable to upgrade to a newer version of OS X, we recommend using an open source browser. Dismiss message
IPR028886 is a Molybdenum cofactor sulfurase.
<p>Molybdenum cofactor sulfurase sulfurates the molybdenum cofactor (MoCo). Sulfation of molybdenum is essential for xanthine dehydrogenase (XDH) and aldehyde oxidase (ADO) enzymes in which molybdenum cofactor is liganded by one oxygen and one sulfur atom in active form [[cite:PUB00043468], [cite:PUB00069597], [cite:PUB00069598], [cite:PUB00069596], [cite:PUB00035522], [cite:PUB00069600]]. This entry also includes its plant homologue, LOS5/ABA3. In plants, the sulfurylated MoCo is a cofactor of ABA-aldehyde oxidase that functions in the last step of ABA biosynthesis [[cite:PUB00069702]].</p>
This description is obtained from EB-eye REST.
GO predictions are based solely on the InterPro-to-GO mappings published by EMBL-EBI, which are in turn based on the mapping of predicted domains to the InterPro dataset. The InterPro-to-GO mapping was last updated on , while the GO metadata was last updated on .
| GO term | Namespace | Name | Definition | Relationships |
|---|---|---|---|---|
| Biological process | Mo-molybdopterin cofactor biosynthetic process | The chemical reactions and pathways resulting in the formation of the Mo-molybdopterin cofactor, essential for the catalytic activity of some enzymes. The cofactor consists of a mononuclear molybdenum (Mo) ion coordinated by one or two molybdopterin ligands. | ||
| Molecular function | Mo-molybdopterin cofactor sulfurase activity | Catalysis of the sulfurylation of the desulfo form of molybdenum cofactor (MoCo), a cofactor required for the activity of some enzymes, such as aldehyde oxidase. |
| Transcript | Name | Description | Predicted domains | Domain count |
|---|---|---|---|---|
| – | PREDICTED: molybdenum cofactor sulfurase-like [Cicer arietinum] gi|502146463|ref|XP_004506463.1| | 18 | ||
| – | Molybdenum cofactor sulfurase; TAIR: AT1G16540.1 molybdenum cofactor sulfurase (LOS5) (ABA3); Swiss-Prot: sp|Q9C5X8|MOCOS_ARATH Molybdenum cofactor sulfurase; TrEMBL-Plants: tr|I1KZR5|I1KZR5_SOYBN Molybdenum cofactor sulfurase; Found in the gene: LotjaGi3g1v0054500 | 19 | ||
| – | Molybdenum cofactor sulfurase; TAIR: AT1G16540.1 molybdenum cofactor sulfurase (LOS5) (ABA3); Swiss-Prot: sp|Q9C5X8|MOCOS_ARATH Molybdenum cofactor sulfurase; TrEMBL-Plants: tr|K7LB25|K7LB25_SOYBN Molybdenum cofactor sulfurase; Found in the gene: LotjaGi3g1v0054500 | 18 |
A list of co-occurring predicted domains within the L. japonicus gene space:
| Predicted domain | Source | Observations | Saturation (%) |
|---|---|---|---|
| SSF53383 | SUPERFAMILY | 1 | 33.33 |