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IPR028923 is a SAICAR synthetase/ADE2, N-terminal.
<p>Phosphoribosylaminoimidazole-succinocarboxamide synthase ([ec:6.3.2.6]) (SAICAR synthetase) catalyses the seventh step in the<i>de novo</i>purine biosynthetic pathway; the ATP-dependent conversion of 5'-phosphoribosyl-5-aminoimidazole-4-carboxylic acid and aspartic acid to SAICAR [[cite:PUB00004940]].</p> <p>This domain can be found in SAICAR synthetases as a monofunctional protein from the bacteria (purC), fungi (ADE1) and plants (Pur7). In animals, this domain can be found in the N-terminal domain of a multifunctional enzyme (ADE2) possessing both the SAICAR synthetase and the phosphoribosylaminoimidazole carboxylase (AIR carboxylase) activity.</p>
This description is obtained from EB-eye REST.
Transcript | Name | Description | Predicted domains | Domain count |
---|---|---|---|---|
– | PREDICTED: phosphoribosylaminoimidazole-succinocarboxamide synthase, chloroplastic-like [Cicer arietinum] gi|502144710|ref|XP_004505724.1| | 12 | ||
– | PREDICTED: phosphoribosylaminoimidazole-succinocarboxamide synthase, chloroplastic-like [Cicer arietinum] gi|502144710|ref|XP_004505724.1| | 14 | ||
– | PREDICTED: phosphoribosylaminoimidazole-succinocarboxamide synthase, chloroplastic-like [Glycine max] gi|356552941|ref|XP_003544818.1| | 9 | ||
– | Phosphoribosylaminoimidazole-succinocarboxamide synthase; TAIR: AT3G21110.1 purin 7; Swiss-Prot: sp|Q07463|PUR7_VIGAC Phosphoribosylaminoimidazole-succinocarboxamide synthase, chloroplastic; TrEMBL-Plants: tr|I1MAX9|I1MAX9_SOYBN Uncharacterized protein; Found in the gene: LotjaGi1g1v0140400 | 14 |
A list of co-occurring predicted domains within the L. japonicus gene space:
Predicted domain | Source | Observations | Saturation (%) |
---|---|---|---|
mobidb-lite | MobiDBLite | 1 | 25.00 |