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IPR030664

Description

IPR030664 is a FAD-dependent oxidoreductase SdhA/FrdA/AprA.

<p>Two distinct, membrane-bound, FAD-containing enzymes are responsible for the catalysis of fumarate and succinate interconversion; the fumarate reductase is used in anaerobic growth, and the succinate dehydrogenase is used in aerobic growth [[cite:PUB00033856]]. Succinate dehydrogenase (Sdh), a primary respiratory dehydrogenase, catalyses electron transfer from succinate to membrane-bound quinone. Fumarate reductase (Frd) catalyses the opposite reaction.</p> <p>The enzyme complex consists at least of four subunits. The hydrophilic catalytic domain consists of a flavoprotein that contains covalently bound FAD and an active site of the enzyme [[cite:PUB00073564], [cite:PUB00002711]].</p> <p>Adenylylsulphate (APS) reductase catalyses reversibly the two-electron reduction of APS to sulphite and AMP during dissimilatory sulphate reduction or sulphur oxidation. Found in several bacterial lineages and in Archaeoglobales, APS reductase is a heterodimer composed of an alpha subunit containing a noncovalently bound FAD, and a beta subunit containing two [4Fe-4S] clusters. The alpha subunit of APS reductase shares a common evolutionary origin with fumarate reductase/succinate dehydrogenase flavoproteins [[cite:PUB00017742]].</p>

This description is obtained from EB-eye REST.

Associated GO terms

Unable to find any GO terms for the transcript with the identifier.

Co-occuring domains 1

A list of co-occurring predicted domains within the L. japonicus gene space:

Predicted domain Source Observations Saturation (%)
TIGR01816 TIGRFAM 1 100.00