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IPR032862 is a Alpha-ketoglutarate-dependent dioxygenase alkB homologue 6.
<p>This entry represents a family of AlkB homologs. Based on similarity with E. coli AlkB, nine mammalian AlkB homologues have been identified. Like E. coli AlkB, ALKBH2 and ALKBH3 have been shown to possess DNA repair activity. However, findings suggest a wide functional diversity for other mammalian AlkB proteins, with substrates ranging from DNA and RNA to protein [[cite:PUB00076917], [cite:PUB00076946]].</p> <p>AlkB homologue 6 (ALKBH6) is a probable dioxygenase that requires molecular oxygen, alpha-ketoglutarate and iron. Its function is not known.</p>
This description is obtained from EB-eye REST.
| Transcript | Name | Description | Predicted domains | Domain count |
|---|---|---|---|---|
| – | PREDICTED: probable alpha-ketoglutarate-dependent dioxygenase ABH6-like [Glycine max] gi|356559947|ref|XP_003548257.1| | 9 | ||
| – | RNA-binding (RRM/RBD/RNP motifs) family protein; TAIR: AT4G20350.2 oxidoreductase; Swiss-Prot: sp|Q3KRA9|ALKB6_HUMAN Alpha-ketoglutarate-dependent dioxygenase alkB homolog 6; TrEMBL-Plants: tr|I3SBA3|I3SBA3_LOTJA Uncharacterized protein; Found in the gene: LotjaGi2g1v0165400 | 9 |
A list of co-occurring predicted domains within the L. japonicus gene space:
| Predicted domain | Source | Observations | Saturation (%) |
|---|---|---|---|
| SSF51197 | SUPERFAMILY | 1 | 50.00 |