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IPR033060 is a Integrator complex subunit 7.
<p>Integrator complex subunit 7 (INTS7) is a component of the integrator complex, a complex that is recruited to the U1 and U2 snRNA genes and mediates the snRNAs' 3' end processing. The integrator complex interacts with the C-terminal tail of the largest subunit of RNA-polymerase II to promote 3'-snRNA processing [[cite:PUB00045283]]. In zebrafish, C. elegans and Drosophila, INTS7 has been found to be essential for normal development [[cite:PUB00053803], [cite:PUB00077569], [cite:PUB00035147], [cite:PUB00077570]].</p>
This description is obtained from EB-eye REST.
GO predictions are based solely on the InterPro-to-GO mappings published by EMBL-EBI, which are in turn based on the mapping of predicted domains to the InterPro dataset. The InterPro-to-GO mapping was last updated on , while the GO metadata was last updated on .
| GO term | Namespace | Name | Definition | Relationships |
|---|---|---|---|---|
| Biological process | SnRNA processing | Any process involved in the conversion of a primary small nuclear RNA (snRNA) transcript into a mature snRNA molecule. | ||
| Cellular component | Integrator complex | A protein complex that stably associates with the C-terminus of RNA polymerase II and mediates 3'-end processing of small nuclear RNAs generated by RNA polymerase II. |
| Transcript | Name | Description | Predicted domains | Domain count |
|---|---|---|---|---|
| – | CM0545.610.nc [Lotus japonicus] gi|164564748|dbj|BAF98228.1| | 5 | ||
| – | Integrator complex subunit 7; TAIR: AT4G20060.1 ARM repeat superfamily protein; Swiss-Prot: sp|Q5ZL91|INT7_CHICK Integrator complex subunit 7; TrEMBL-Plants: tr|B0BLJ3|B0BLJ3_LOTJA CM0545.590.nc protein; Found in the gene: LotjaGi1g1v0063600_LC | 2 | ||
| – | Integrator complex subunit 7; TAIR: AT4G20060.1 ARM repeat superfamily protein; Swiss-Prot: sp|Q5ZL91|INT7_CHICK Integrator complex subunit 7; TrEMBL-Plants: tr|B0BLJ2|B0BLJ2_LOTJA CM0545.610.nc protein; Found in the gene: LotjaGi1g1v0063900 | 4 | ||
| – | Integrator complex subunit 7; TAIR: AT4G20060.1 ARM repeat superfamily protein; Swiss-Prot: sp|Q5ZL91|INT7_CHICK Integrator complex subunit 7; TrEMBL-Plants: tr|B0BLJ2|B0BLJ2_LOTJA CM0545.610.nc protein; Found in the gene: LotjaGi1g1v0063900 | 4 | ||
| – | Integrator complex subunit 7; TAIR: AT4G20060.1 ARM repeat superfamily protein; Swiss-Prot: sp|Q5ZL91|INT7_CHICK Integrator complex subunit 7; TrEMBL-Plants: tr|B0BLJ2|B0BLJ2_LOTJA CM0545.610.nc protein; Found in the gene: LotjaGi1g1v0064400_LC | 2 | ||
| – | Integrator complex subunit 7; TAIR: AT4G20060.1 ARM repeat superfamily protein; Swiss-Prot: sp|Q5ZL91|INT7_CHICK Integrator complex subunit 7; TrEMBL-Plants: tr|B0BLJ2|B0BLJ2_LOTJA CM0545.610.nc protein; Found in the gene: LotjaGi1g1v0064500 | 4 | ||
| – | Integrator complex subunit 7; TAIR: AT4G20060.1 ARM repeat superfamily protein; Swiss-Prot: sp|Q5ZL91|INT7_CHICK Integrator complex subunit 7; TrEMBL-Plants: tr|B0BLJ2|B0BLJ2_LOTJA CM0545.610.nc protein; Found in the gene: LotjaGi1g1v0064500 | 4 | ||
| – | Integrator complex subunit 7; TAIR: AT4G20060.1 ARM repeat superfamily protein; Swiss-Prot: sp|Q5ZL91|INT7_CHICK Integrator complex subunit 7; TrEMBL-Plants: tr|B0BLJ2|B0BLJ2_LOTJA CM0545.610.nc protein; Found in the gene: LotjaGi3g1v0453300_LC | 2 |
A list of co-occurring predicted domains within the L. japonicus gene space:
| Predicted domain | Source | Observations | Saturation (%) |
|---|---|---|---|
| PTHR13322 | PANTHER | 1 | 12.50 |