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IPR034088 is a Pla a 1-like.
<p>This entry includes pollen allergen Pla a 1 protein from Platanus acerifolia (London plane tree) and its homologues, including pectinesterase inhibitor 12 from Arabidopsis [[cite:PUB00084376]].</p> <p>The major Platanus acerifolia pollen allergen Pla a 1 belongs to a class of allergens related to proteinaceous invertase and pectin methylesterase inhibitors. Platanus acerifolia is an important cause of pollinosis; Pla a 1 has a prevalence of about 80% among plane tree pollen-allergic patients [[cite:PUB00082639]]. Recombinant Pla a 1 binds IgE in vitro, similar to its natural counterpart, rendering it suitable for specific diagnosis and structural studies [[cite:PUB00082640]].</p> <p>Invertase inhibitors are structurally similar to those of pectin methylesterase (PMEIs), an enzyme that is involved in the control of pectin metabolism and is structurally unrelated to invertases [[cite:PUB00083110]]. All inhibitors share a size of about 18kDa, two strictly conserved disulfide bridges and only moderate sequence homology (about 20% sequence identity) [[cite:PUB00040033]].</p>
This description is obtained from EB-eye REST.
| Transcript | Name | Description | Predicted domains | Domain count |
|---|---|---|---|---|
| – | Invertase/pectin methylesterase inhibitor family protein; TAIR: AT5G46940.1 Plant invertase/pectin methylesterase inhibitor superfamily protein; Swiss-Prot: sp|Q8GT41|PLA1_PLAAC Putative invertase inhibitor; TrEMBL-Plants: tr|G7LDE9|G7LDE9_MEDTR Plant invertase/pectin methylesterase inhibitor; Found in the gene: LotjaGi3g1v0072200 | 18 | ||
| – | Invertase/pectin methylesterase inhibitor family protein; TAIR: AT5G38610.1 Plant invertase/pectin methylesterase inhibitor superfamily protein; Swiss-Prot: sp|Q8GT41|PLA1_PLAAC Putative invertase inhibitor; TrEMBL-Plants: tr|I3SG04|I3SG04_LOTJA Uncharacterized protein; Found in the gene: LotjaGi4g1v0191300 | 18 | ||
| – | Plant invertase/pectin methylesterase inhibitor; TAIR: AT5G46960.1 Plant invertase/pectin methylesterase inhibitor superfamily protein; Swiss-Prot: sp|Q8GT41|PLA1_PLAAC Putative invertase inhibitor; TrEMBL-Plants: tr|I3T7D3|I3T7D3_LOTJA Uncharacterized protein; Found in the gene: LotjaGi4g1v0191500 | 19 | ||
| – | Plant invertase/pectin methylesterase inhibitor protein; TAIR: AT3G17220.1 pectin methylesterase inhibitor 2; Swiss-Prot: sp|Q9LUV1|PMEI2_ARATH Pectinesterase inhibitor 2; TrEMBL-Plants: tr|A0A151S715|A0A151S715_CAJCA Uncharacterized protein; Found in the gene: LotjaGi5g1v0289100 | 18 |
A list of co-occurring predicted domains within the L. japonicus gene space:
| Predicted domain | Source | Observations | Saturation (%) |
|---|---|---|---|
| cd15795 | CDD | 1 | 25.00 |