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IPR037099 is a Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal domain superfamily.
<p>This entry represents a domain superfamily with a spectrin-repeat-like fold consisting of three helices in a closed bundle with a left-handed twist. This domain superfamily is found in the succinate dehydrogenase/fumarate reductase oxidoreductase family of proteins, such as:</p> <ul> <li>L-aspartate oxidase ([ec:1.4.3.16]), a flavoenzyme component of the bacterial quinolinate synthase system that catalyses the conversion of L-aspartate to oxaloacetate, the first step in the de novo biosynthesis of NAD+ [[cite:PUB00026780], [cite:PUB00023955]].</li> <li>Fumarate reductase, which is part of the quinol-fumarate reductase (QFR) respiratory complex that catalyses the terminal step of anaerobic respiration when fumarate acts as the terminal electron acceptor [[cite:PUB00013184]].</li> <li>Succinate dehydrogenase (SQR; [ec:1.3.5.1]), an iron-sulphur flavoenzyme from bacteria that is analogous to the mitochondrial respiratory complex II, forming part of the electron transport pathway from the electron acceptor (succinate) to the terminal donor (ubiquinone) [[cite:PUB00015752]].</li> <li>Adenylylsulphate reductase A subunit ([ec:1.8.4]), an iron-sulphur flavoenzyme that catalyses the reversible reduction of adenosine-5'-phosphate (APS) to sulphite and AMP [[cite:PUB00026455]].</li> </ul>
This description is obtained from EB-eye REST.
GO predictions are based solely on the InterPro-to-GO mappings published by EMBL-EBI, which are in turn based on the mapping of predicted domains to the InterPro dataset. The InterPro-to-GO mapping was last updated on , while the GO metadata was last updated on .
| GO term | Namespace | Name | Definition | Relationships |
|---|---|---|---|---|
| Molecular function | Oxidoreductase activity | Catalysis of an oxidation-reduction (redox) reaction, a reversible chemical reaction in which the oxidation state of an atom or atoms within a molecule is altered. One substrate acts as a hydrogen or electron donor and becomes oxidized, while the other acts as hydrogen or electron acceptor and becomes reduced. | ||
| Biological process | Oxidation-reduction process | A metabolic process that results in the removal or addition of one or more electrons to or from a substance, with or without the concomitant removal or addition of a proton or protons. |
| Transcript | Name | Description | Predicted domains | Domain count |
|---|---|---|---|---|
| – | Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial; TAIR: AT5G14760.1 L-aspartate oxidase; Swiss-Prot: sp|Q94AY1|NADB_ARATH L-aspartate oxidase, chloroplastic; TrEMBL-Plants: tr|A0A0B2R629|A0A0B2R629_GLYSO L-aspartate oxidase; Found in the gene: LotjaGi2g1v0246300 | 18 | ||
| – | Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial; TAIR: AT5G14760.1 L-aspartate oxidase; Swiss-Prot: sp|Q94AY1|NADB_ARATH L-aspartate oxidase, chloroplastic; TrEMBL-Plants: tr|I1K1F9|I1K1F9_SOYBN L-aspartate oxidase; Found in the gene: LotjaGi2g1v0246300 | 17 | ||
| – | Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial; TAIR: AT5G66760.1 succinate dehydrogenase 1-1; Swiss-Prot: sp|O82663|SDHA1_ARATH Succinate dehydrogenase [ubiquinone] flavoprotein subunit 1, mitochondrial; TrEMBL-Plants: tr|I1JCQ7|I1JCQ7_SOYBN Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial; Found in the gene: LotjaGi4g1v0116700 | 23 | ||
| – | Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial; TAIR: AT5G66760.1 succinate dehydrogenase 1-1; Swiss-Prot: sp|O82663|SDHA1_ARATH Succinate dehydrogenase [ubiquinone] flavoprotein subunit 1, mitochondrial; TrEMBL-Plants: tr|I1JCQ7|I1JCQ7_SOYBN Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial; Found in the gene: LotjaGi4g1v0116700 | 23 | ||
| – | Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial; TAIR: AT5G66760.1 succinate dehydrogenase 1-1; Swiss-Prot: sp|O82663|SDHA1_ARATH Succinate dehydrogenase [ubiquinone] flavoprotein subunit 1, mitochondrial; TrEMBL-Plants: tr|I1JCQ7|I1JCQ7_SOYBN Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial; Found in the gene: LotjaGi4g1v0116700 | 23 |
A list of co-occurring predicted domains within the L. japonicus gene space:
| Predicted domain | Source | Observations | Saturation (%) |
|---|---|---|---|
| TIGR01816 | TIGRFAM | 1 | 20.00 |