Your browser is unable to support new features implemented in HTML5 and CSS3 to render this site as intended. Your experience may suffer from functionality degradation but the site should remain usable. We strongly recommend the latest version of Google Chrome, OS X Safari or Mozilla Firefox. As Safari is bundled with OS X, if you are unable to upgrade to a newer version of OS X, we recommend using an open source browser. Dismiss message
IPR037175 is a Kynurenine formamidase superfamily.
<p>Kynurenine formamidase catalyses the hydrolysis of N-formyl-L-kynurenine to L-kynurenine, the second step in the kynurenine pathway of tryptophan degradation [[cite:PUB00043036]]. The proteins contain a conserved motif HXGTHXDXPXH that is likely to form a part of the active site.</p> <p>Structurally, it contains a mixed β-sheet close barrel fold.</p>
This description is obtained from EB-eye REST.
GO predictions are based solely on the InterPro-to-GO mappings published by EMBL-EBI, which are in turn based on the mapping of predicted domains to the InterPro dataset. The InterPro-to-GO mapping was last updated on , while the GO metadata was last updated on .
| GO term | Namespace | Name | Definition | Relationships |
|---|---|---|---|---|
| Molecular function | Arylformamidase activity | Catalysis of the reaction: N-formyl-L-kynurenine + H2O = formate + L-kynurenine. | ||
| Biological process | Tryptophan catabolic process to kynurenine | The chemical reactions and pathways resulting in the breakdown of tryptophan into other compounds, including kynurenine. |
| Transcript | Name | Description | Predicted domains | Domain count |
|---|---|---|---|---|
| – | Kynurenine formamidase; TAIR: AT4G35220.1 Cyclase family protein; Swiss-Prot: sp|Q2N5X0|KYNB_ERYLH Kynurenine formamidase; TrEMBL-Plants: tr|A0A151U7S0|A0A151U7S0_CAJCA Kynurenine formamidase; Found in the gene: LotjaGi5g1v0329100 | 15 | ||
| – | Kynurenine formamidase-like protein; TAIR: AT4G35220.1 Cyclase family protein; Swiss-Prot: sp|Q2S2F5|KYNB_SALRD Kynurenine formamidase; TrEMBL-Plants: tr|I3SIK3|I3SIK3_MEDTR Kynurenine formamidase-like protein; Found in the gene: LotjaGi5g1v0329200 | 14 | ||
| – | Kynurenine formamidase-like protein; TAIR: AT4G35220.1 Cyclase family protein; Swiss-Prot: sp|Q2N5X0|KYNB_ERYLH Kynurenine formamidase; TrEMBL-Plants: tr|I3SIK3|I3SIK3_MEDTR Kynurenine formamidase-like protein; Found in the gene: LotjaGi5g1v0329200 | 14 | ||
| – | Kynurenine formamidase-like protein; TAIR: AT4G35220.1 Cyclase family protein; Swiss-Prot: sp|Q2S2F5|KYNB_SALRD Kynurenine formamidase; TrEMBL-Plants: tr|I3SIK3|I3SIK3_MEDTR Kynurenine formamidase-like protein; Found in the gene: LotjaGi5g1v0329200 | 14 |
A list of co-occurring predicted domains within the L. japonicus gene space:
| Predicted domain | Source | Observations | Saturation (%) |
|---|---|---|---|
| SignalP-noTM | SignalP_GRAM_NEGATIVE | 1 | 25.00 |