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IPR037992

Source: InterPro

Description

IPR037992 is a TRAPP complex, Trs33 subunit.

<p>Trs33 (corresponding to human homologues TRAPPC6A and TRAPPC6B) is a subunit of the trafficking protein particle complex (TRAPP). Transport protein particle (TRAPP) complexes are multimeric guanine nucleotide-exchange factors for the GTPase Ypt1. Trs33 is one of the core subunits of TRAPP complexes which play a key role in the regulation of ER-to-Golgi and intra-Golgi transport by tethering the vesicle membrane to the target membrane [[cite:PUB00080273]]. In yeast, it is a core component of TRAPP complexes I, II and IV. Complex IV is thought to be involved in autophagy [[cite:PUB00088018]]. In mammals, mutations in TRAPPC6a cause mosaic loss of coat pigment [[cite:PUB00088012]].</p>

This description is obtained from EB-eye REST.

Associated GO terms

GO predictions are based solely on the InterPro-to-GO mappings published by EMBL-EBI, which are in turn based on the mapping of predicted domains to the InterPro dataset. The InterPro-to-GO mapping was last updated on , while the GO metadata was last updated on .

GO term Namespace Name Definition Relationships
GO:0043087
Biological process Regulation of GTPase activity Any process that modulates the rate of GTP hydrolysis by a GTPase.
Subterm of
GO:0048193
Biological process Golgi vesicle transport The directed movement of substances into, out of or within the Golgi apparatus, mediated by vesicles.
Subterm of

Associated Lotus transcripts 1

Transcript Name Description Predicted domains Domain count
LotjaGi2g1v0165300.1
– Trafficking protein particle complex subunit 6B; TAIR: AT3G05000.1 Transport protein particle (TRAPP) component; Swiss-Prot: sp|Q32L78|TPC6B_BOVIN Trafficking protein particle complex subunit 6B; TrEMBL-Plants: tr|I1JRI0|I1JRI0_SOYBN Uncharacterized protein; Found in the gene: LotjaGi2g1v0165300
Domains
9

Co-occuring domains 1

A list of co-occurring predicted domains within the L. japonicus gene space:

Predicted domain Source Observations Saturation (%)
cd14944 CDD 1 100.00